Protein Info for LRK55_RS13930 in Rhodanobacter denitrificans MT42

Annotation: TetR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 209 transmembrane" amino acids 84 to 103 (20 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details PF00440: TetR_N" amino acids 21 to 65 (45 residues), 32.9 bits, see alignment 1.1e-11 PF17932: TetR_C_24" amino acids 85 to 171 (87 residues), 39.5 bits, see alignment E=1.6e-13 PF17938: TetR_C_29" amino acids 87 to 162 (76 residues), 28.4 bits, see alignment E=3.9e-10 PF14246: TetR_C_7" amino acids 108 to 188 (81 residues), 29.5 bits, see alignment E=1.6e-10 PF13977: TetR_C_6" amino acids 120 to 182 (63 residues), 27.4 bits, see alignment E=8.2e-10

Best Hits

KEGG orthology group: None (inferred from 76% identity to adk:Alide2_1924)

Predicted SEED Role

"Transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (209 amino acids)

>LRK55_RS13930 TetR family transcriptional regulator (Rhodanobacter denitrificans MT42)
MATNIPRKHLPADERRAVTVEAVVKLAAEQNPSEITTAAIATSMKLTQGALFRHFPNKDA
IWQAVMEWVADHLLARVERAARDAASPLAALEAMFMAHIGFVAEHPGVPRMLFGELQRAE
DTAAKRMVQTMIRRYGERLRALIEEGQAAGELDPQLDPAAAATLFIGSIQGLVMQALLAG
DTRHMRKEAAGAFAIYRRGIARAARRSRT