Protein Info for LRK55_RS13100 in Rhodanobacter denitrificans MT42

Annotation: gamma-glutamyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 574 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR00066: gamma-glutamyltransferase" amino acids 48 to 565 (518 residues), 435.8 bits, see alignment E=1e-134 PF01019: G_glu_transpept" amino acids 61 to 567 (507 residues), 533.7 bits, see alignment E=2.8e-164

Best Hits

KEGG orthology group: K00681, gamma-glutamyltranspeptidase [EC: 2.3.2.2] (inferred from 57% identity to psu:Psesu_1196)

Predicted SEED Role

"Gamma-glutamyltranspeptidase (EC 2.3.2.2)" in subsystem Glutathione: Biosynthesis and gamma-glutamyl cycle or Utilization of glutathione as a sulphur source (EC 2.3.2.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (574 amino acids)

>LRK55_RS13100 gamma-glutamyltransferase (Rhodanobacter denitrificans MT42)
MRFSLNWAVLSLSLLLAGGAAFAADGAPKTAPLAPAHAASLRPGHAAVASANFHATEAGL
EVLAKGGNAFDAAVAVASTLSIVEPESSGTGGGFMAVLHRAKDGRNIFIDARETAPAAVN
PKDYLNPDGSPNRDTALRGPLSAGIPGQPAGLVLLSSRYGRLPLAQSLAPAIRIARDGFQ
PDERLRHAIAGTQKDLERWPASAAKYLPGGKPPAEGATWRDPDQARTLELLAAHGRDGFY
RGETAQKLVKAVHAAGGNWTLADLANYQAKERTPISVDYRGYQIITAPPPSSGGVAIAEI
LNILSGYDLTKMDAATRVHYIVEAMRRAFRDHNDYLGDPDFVQMPLDMLLSPYYAAGLRQ
SILPDKATPSSMLPRAEAPEPGMHTTHFSIIDADGNMAAVTSTVNYTMGSGFVAAGTGVL
LNDEMDDFALVPNKPNVYGLLGSTANAPKGGKRMLSSMSPSIVIGAERTAVIGSPGGSTI
ITQVLEGILHFIDGESAQQIAAHKRFHHQYLPDVVMVEDGTFDAATGEALTKMGYTLKPR
ESWGFMNVVTWDRKTNKLDAASDPRRPSGLGKVQ