Protein Info for LRK55_RS12765 in Rhodanobacter denitrificans MT42

Annotation: glycoside hydrolase family 31 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 749 PF01055: Glyco_hydro_31_2nd" amino acids 209 to 511 (303 residues), 227 bits, see alignment E=6.4e-71 PF21365: Glyco_hydro_31_3rd" amino acids 522 to 609 (88 residues), 83.1 bits, see alignment E=2.3e-27 PF17137: DUF5110" amino acids 627 to 695 (69 residues), 56.6 bits, see alignment E=3.3e-19

Best Hits

Predicted SEED Role

"Alpha-glucosidase (EC 3.2.1.20)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (749 amino acids)

>LRK55_RS12765 glycoside hydrolase family 31 protein (Rhodanobacter denitrificans MT42)
MDTTVRHGISIDTQGGQLIVRFVTPGIVHVQHPHAAAAPALVLDPTARPGAFDARRSDDG
ANGPVLASERGSVRWDRQQRQLRIDDAQQRPLLQIDLDAAPSGALNLRHDPRDALYGIGG
YNATEDASAGMLRNGKQVAMSGEQGHAGAPFVWSSAGYGVLLDSDGASFTLAPGAISAVD
AARRQADYYILLGTPTQIFAELAQLSGRTPLFPKWAMGFTNSQWGIDQQELLQIVDTYRA
KHIPLDNITLDFDWKAWGEDDYGEFRWNPAKFPDGPSGALKKQMDARGIRLTGIMKPRIH
LDTVEGRYASAHGFWVPDEKVSDDYFSHKPVKDIDFDLPAARRWFGELAIKYGYDHGIAG
WWNDEADTVGSDTEFMNMQRALYDSQRAVSNLRVWSINRNFWLGSQRYAYGLWSGDIPTG
FASMAGQRARMLSAINVGAMQWGMDGGGFKDGTPTPENYARWIQFGAFTPIFRVHGELGQ
KRQPWVYGPVAEKAATDAIRLRYALIPYIYSYEHARRATGVGLVRPLLFDWPHDPKLRND
VDSWLFGDWLLASPVVAEGQTAKDIYLPAGRWTDWFSGKTYDGGQTIRLAIDSKTWSDIP
LFVREGAIIPTRPDPVDYVGERPLTRLDVDVFPAAQRSTFDYYDDDGASYDYERGAYFLQ
PLSVQRQGATVQLDIGKASGSFKPALRFYLLKIHGGAAARVSGKLKSFPDLEALQQSGGE
GWASGRDRYGEVTWVRVTAGHATRITLAM