Protein Info for LRK55_RS12710 in Rhodanobacter denitrificans MT42

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF00356: LacI" amino acids 9 to 49 (41 residues), 55 bits, see alignment 1.1e-18 PF00532: Peripla_BP_1" amino acids 81 to 318 (238 residues), 70.4 bits, see alignment E=3.6e-23 PF13407: Peripla_BP_4" amino acids 81 to 320 (240 residues), 37.5 bits, see alignment E=4e-13 PF13377: Peripla_BP_3" amino acids 179 to 338 (160 residues), 125.2 bits, see alignment E=5.9e-40

Best Hits

KEGG orthology group: None (inferred from 71% identity to psu:Psesu_1114)

Predicted SEED Role

"Transcriptional regulator of maltose utilization, LacI family" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (340 amino acids)

>LRK55_RS12710 LacI family DNA-binding transcriptional regulator (Rhodanobacter denitrificans MT42)
MKAKATSIDIAHLAGVSQATVSRALRGSPLVNEETRRRIQAAAEQLNYKVDKNASNLRRM
HSGTLALLFFEDPTADESHINPFFLSMLGSITRACALQGYDLLISFQQFSHDWHADFADS
KKADGLILLGYGDYLAYTDKLEKLVAQGTRFVRWGAVLADQPGVSIGCDNFRGGQAVAGH
LLERGCRRIAFLGDASSHYPEFFGRYRGYVDALQQAGVAVDPALQENAESTERSGYEAMR
SLILREAGFDAVFAASDLIAIGAMRALSDHGLRVPQDVALAGFDDIPMASFVNPPLTTVL
QDTKQAGEVLVDSLLGLIRGGPVDSEVLPVKLVVRRSSLR