Protein Info for LRK55_RS11680 in Rhodanobacter denitrificans MT42

Annotation: drug/metabolite exporter YedA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 51 to 69 (19 residues), see Phobius details amino acids 81 to 102 (22 residues), see Phobius details amino acids 109 to 129 (21 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 165 to 182 (18 residues), see Phobius details amino acids 194 to 212 (19 residues), see Phobius details amino acids 225 to 246 (22 residues), see Phobius details amino acids 257 to 275 (19 residues), see Phobius details amino acids 281 to 299 (19 residues), see Phobius details PF00892: EamA" amino acids 25 to 153 (129 residues), 72.1 bits, see alignment E=2.7e-24 amino acids 163 to 297 (135 residues), 76.8 bits, see alignment E=9.1e-26

Best Hits

Swiss-Prot: 50% identical to YEDA_ECO57: Uncharacterized inner membrane transporter YedA (yedA) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 59% identity to psu:Psesu_2666)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>LRK55_RS11680 drug/metabolite exporter YedA (Rhodanobacter denitrificans MT42)
MSDTPAPVAAATPRSLSDPRFLIPLALLALYVIWGSTYLGIRFALESWPPFLLAGVRFLA
AGVALYGFLRWRGMAPPTRLQWRNAAITGLLLLGLGNGLVCFAEQRVSSGIAAVAVASMP
LFAALFSGMYGEWPHRRESIGLAIGFAGVIVLNLGSSLAGSSTGAVALLVAAAAWAFGSV
WSRRQVMPPGPMNTAAQMICGSIALLGFALLSGERLPLHPSLRSTLAILYLAVFGSIIAF
SAYLYVLRHARPALATSYAYVNPPVAVLFGVLLAGEHVGPFDLAGMAIILAGVAVITLAK
SKGNTAKP