Protein Info for LRK55_RS11380 in Rhodanobacter denitrificans MT42

Annotation: chloride channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 640 transmembrane" amino acids 49 to 71 (23 residues), see Phobius details amino acids 108 to 127 (20 residues), see Phobius details amino acids 205 to 230 (26 residues), see Phobius details amino acids 242 to 263 (22 residues), see Phobius details amino acids 275 to 294 (20 residues), see Phobius details amino acids 314 to 331 (18 residues), see Phobius details amino acids 351 to 371 (21 residues), see Phobius details amino acids 381 to 402 (22 residues), see Phobius details amino acids 412 to 436 (25 residues), see Phobius details amino acids 443 to 464 (22 residues), see Phobius details PF00654: Voltage_CLC" amino acids 119 to 459 (341 residues), 274.1 bits, see alignment E=1.8e-85 PF00571: CBS" amino acids 496 to 549 (54 residues), 29.8 bits, see alignment 6.1e-11 amino acids 559 to 613 (55 residues), 48.5 bits, see alignment 8.7e-17

Best Hits

KEGG orthology group: None (inferred from 60% identity to scl:sce0443)

Predicted SEED Role

"Chloride channel protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (640 amino acids)

>LRK55_RS11380 chloride channel protein (Rhodanobacter denitrificans MT42)
MTPATDTPVEHTDVRTVGSTDALPIAPALGLSLDAARMPRKSTLVTRRILLISVLAVILG
VVAAYVAQLLMLTINLITDLCFYGRVSDVIGPHARTGSFVLSPADNQLGAWVILIPVVGG
LLAGVMARWGSRAIQGHGIPEAMEQILTNESNIPARITWLKPLSSAFAIGTGGPFGAEGP
IISTGGAMGSLIGQLLRVTANERKVLLAAGAAAGMAAVFGAPVASLVLAVELLLFELRPR
SLIPVALAAVTAVGVRYATYGAAPVFPMPDVLQPGGWALISFVLIGGLVGYASVWVTKAV
YGVEDMFEKLPVHWMWWPALGALVAGFVGWIEPRTLGVGYDNIDALVQGHFGLTMLLIFG
ALKFVSWVIALGSGTSGGTLAPLFMIGGSLGAVIGIGINHFLPGFGIDPRIAALVGMAAI
FAGSSRALLTAVVFAFETTRQPASLLPLLGGCTAAYLISALLMRNTIMTEKIARRGVKVP
SEYAADYLEQVSVGTACSRNVTTLRTTQTLAEVRRWLADEASHTQHQGYPVVDEQGRVQG
VLTRRSLLDPQWHYTLALGELLTRPPIAVTEDHSLREAADHMVAESVGRLVVVSKNDPHR
LVGIITRGDILAAHARRLREARFKGRHIKLGKSEKPAGAA