Protein Info for LRK55_RS10100 in Rhodanobacter denitrificans MT42

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 transmembrane" amino acids 31 to 53 (23 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 85 to 103 (19 residues), see Phobius details amino acids 112 to 130 (19 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 196 to 355 (160 residues), 135.2 bits, see alignment E=9e-44 PF00990: GGDEF" amino acids 199 to 352 (154 residues), 128.1 bits, see alignment E=1.4e-41

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (356 amino acids)

>LRK55_RS10100 GGDEF domain-containing protein (Rhodanobacter denitrificans MT42)
MHALFKHLRQADDTEQRREYSHYLAQQMGPMIHALMLVGALAYLVAVTASTLVRHSSLPL
WLRLAPLAPLLLVAASTRHVRQPRLLSALTLLCVLLLEIGINLNGMDDMHRQSVVLPGLL
LPVASSVVWLGRWDFVAAMLLCALGPLPMLLFGSADSAQVFQYLVYMAIAIALSTVLRAF
MARTLFEQFRLERQLREQANTDGLTGLLVRNRFLELAQLALGDIHRRQQPACVLYLDADH
FKPLNDDHGHAAGDAALIALATAMRRQMRQGDLIGRIGGEEFAMLLPGLDLQQAGARAEQ
LRQSMHEIRRPDGPLTVSIGVAACGHADEAIETLLARADQAMRQAKRDGRDRVVCA