Protein Info for LRK55_RS08780 in Rhodanobacter denitrificans MT42

Annotation: rhomboid family intramembrane serine protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 71 to 96 (26 residues), see Phobius details amino acids 107 to 126 (20 residues), see Phobius details amino acids 132 to 152 (21 residues), see Phobius details amino acids 165 to 191 (27 residues), see Phobius details amino acids 198 to 216 (19 residues), see Phobius details PF01694: Rhomboid" amino acids 69 to 216 (148 residues), 87.2 bits, see alignment E=6.1e-29

Best Hits

KEGG orthology group: None (inferred from 36% identity to dba:Dbac_1812)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (227 amino acids)

>LRK55_RS08780 rhomboid family intramembrane serine protease (Rhodanobacter denitrificans MT42)
MFVHVETRRRPRWHWATLLVVTVCVMCFVGLALTPATQRVSLLLEWGTVPANIFDPHQAL
LPQLTDPALLRLFTALFIHVTWLHLLSNLLFLAIFGLPGERALGSLRFLLLFAVGGIVAN
LIGALSLTGVRLPIIGCSGAVSAVVGTYVALFPRARLGLVLPLGLYLEFVRVPAFLLIGL
WVLLQLLFSYAGASYGAYVWWAHIGGFLFGVVFALFSRDAIARRLRG