Protein Info for LRK55_RS07425 in Rhodanobacter denitrificans MT42

Annotation: family 20 glycosylhydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 768 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF02838: Glyco_hydro_20b" amino acids 29 to 159 (131 residues), 84.9 bits, see alignment E=1.6e-27 PF00728: Glyco_hydro_20" amino acids 162 to 502 (341 residues), 400.4 bits, see alignment E=1.6e-123 PF13290: CHB_HEX_C_1" amino acids 551 to 601 (51 residues), 36.8 bits, see alignment 6.2e-13 PF13287: Fn3_assoc" amino acids 563 to 600 (38 residues), 31.5 bits, see alignment 3.1e-11

Best Hits

KEGG orthology group: K12373, hexosaminidase [EC: 3.2.1.52] (inferred from 53% identity to xal:XALc_2219)

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (768 amino acids)

>LRK55_RS07425 family 20 glycosylhydrolase (Rhodanobacter denitrificans MT42)
MTRRLILFGCAILALGGAGFVRAAAPPVPALLPLPAQLHVDAGRFTVDARTPIVLADDAA
STRRTGAWLAGLLAHTRGLPLPLQRGAATTARAIVLQRDPAAPVADREGYALDITPQGIR
VSARDDAGLFYGAVTLWQLLTPDAQQGAVELPALSIRDQPRFAWRGLMLDSVRHFQSVAE
IERLLEQMAQHKLNTFHWHLTDDQGWRIQIKRYPELTRIGAWRTSPDAGHDGQPSRYGGY
YTQAQIRRIVAYAAARHITVVPEIDMPGHAQAAVAAYPRFGVTGARPPVSVDWGINPYLY
NVDDATFTFIENVLDEVMALFPSTYIHVGGDEAIKDQWQAAPAVQAKMRALGIASEDALQ
GWFIGRIGQYLDKHGRKLVGWDEILDGDNLPADATVMSWRGTDGAIKAAMMGHDVVLSPA
PQLYFDHVQGDLADEYAGRLGVESLQSVYAFPTVPAVLGAAQAKHVLGVQANVWTEHMPA
FAHVEHAVFPRLDALSEVAWSPATALNWPGFLARLPVQLGRYRAQHVNVADSAFAVEIVT
ERNVALATGRATVALANQAGFGVIRYTLDGSAPTADSPRYDAPLVLQLPVTVRAASFAAD
GSALAAPRERVLDRAGLLGLPGGLLANCPGSDFRLRLQPMPDAPSTQPVYAVNVFDGCQL
FPATRMDEVAAIRVDAVRLPRNFALAHEAKLVVSRPRATPFGELVVHADSCAGVVLASMP
LPDPARGARRFTLQAELPAQQGERALCLIYTAPTDGPLYAIDRVALEP