Protein Info for LRK55_RS07225 in Rhodanobacter denitrificans MT42

Annotation: electron transfer flavoprotein-ubiquinone oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 PF13450: NAD_binding_8" amino acids 13 to 55 (43 residues), 26.4 bits, see alignment 1.4e-09 PF21162: ETFQO_UQ-bd" amino acids 212 to 305 (94 residues), 138.3 bits, see alignment E=2.1e-44 PF05187: ETF_QO" amino acids 444 to 546 (103 residues), 153.2 bits, see alignment E=4.3e-49

Best Hits

KEGG orthology group: K00311, electron-transferring-flavoprotein dehydrogenase [EC: 1.5.5.1] (inferred from 72% identity to bpt:Bpet1787)

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

Compare fitness of predicted isozymes for: 1.5.5.1

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (548 amino acids)

>LRK55_RS07225 electron transfer flavoprotein-ubiquinone oxidoreductase (Rhodanobacter denitrificans MT42)
MSDSTAMEYDVIVVGGGPGGLAAAIRLKQLARERQHDINVCVLEKAPEIGAQILSGCIMD
PRALTELIPDWAERGAPLTLPVAQDRFVFLTQTGTRATPHWLLPPCFRNAGNYVVQLGHV
VHWLGVQAEALGVDVFPGFAAAKVLYDEHGAVCGVETGETGVAKGGTHTDAYESGTQLVA
RYTVFAEGSRGHLGRQLIERFHLDADCDPQSYAIGVKELWEVDPAKAHPGLVMHTAGWPL
DAQTYGGSFLYHLERNLVAVGFVIGTDYRNPTLSPFEEMQRYKTHPAIRTVFDGGKRVAY
GARSLTAGGLASLPKMVFPGGALIGCEAGVLNASRIKGSHAAIKTGMLAADAVFDAVVAG
RSHDELTRYPEALRASWLYRELRKSRNFKQWFHYGRRVATVMTGVEQWLLRGHIPWNLHH
HTPDHARLRPLSECVKIEYPKPDGKLTFDRASSVFLSNTHHDENQPAHLTLKDPAVPVQV
NLAKYGGPEAFYCPAGVYEFVHGPDGAVRLQINAANCVHCKLCDIKDPKQNIVWTTPHGG
EGPIYNGM