Protein Info for LRK55_RS06795 in Rhodanobacter denitrificans MT42

Annotation: DNA primase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 595 TIGR01391: DNA primase" amino acids 5 to 431 (427 residues), 438.4 bits, see alignment E=1.3e-135 PF01807: zf-CHC2" amino acids 6 to 99 (94 residues), 131.3 bits, see alignment E=3.7e-42 PF08275: DNAG_N" amino acids 125 to 265 (141 residues), 118.1 bits, see alignment E=1.1e-37 PF13662: Toprim_4" amino acids 274 to 339 (66 residues), 59.9 bits, see alignment E=9.3e-20 PF01751: Toprim" amino acids 275 to 351 (77 residues), 51.7 bits, see alignment E=3.4e-17 PF13362: Toprim_3" amino acids 275 to 370 (96 residues), 31.3 bits, see alignment E=9.4e-11 PF13155: Toprim_2" amino acids 276 to 363 (88 residues), 60.8 bits, see alignment E=5.5e-20 PF10410: DnaB_bind" amino acids 383 to 434 (52 residues), 52.8 bits, see alignment 1.5e-17 PF08278: DnaG_DnaB_bind" amino acids 460 to 583 (124 residues), 91.8 bits, see alignment E=1.9e-29

Best Hits

KEGG orthology group: K02316, DNA primase [EC: 2.7.7.-] (inferred from 54% identity to xcv:XCV3994)

Predicted SEED Role

"DNA primase (EC 2.7.7.-)" in subsystem DNA-replication or Macromolecular synthesis operon (EC 2.7.7.-)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (595 amino acids)

>LRK55_RS06795 DNA primase (Rhodanobacter denitrificans MT42)
MRGLIPDSFIDELLARVDIVDVIERRVPLKKAGREWTACCPFHNERTPSFYVSPAKQFFH
CFGCGAHGSAVKFLMDYERLEFPDAVEELAQTVGLTVPREGGREAAPREDKTDLYALLDA
AAAWYEGELPRNADAQAYCRKRGLDAETIRRFRLGWAPAGYDGVIKALGNTPRRMELLNE
AGMVASSERGSKYDRFRERLMFPILDRRGRVIAFGGRIIERSGEGSPAPDARTQDARKSD
GPKYLNSPETPLFHKGRELFALWQVKQANPTLARIVVVEGYMDVIALHQAGLPIAVATLG
TATTPEHTEVLFRAAPDVVFCFDGDRAGRAAAWKALESALPRLRDGRQAYFLFLPDGEDP
DSLVRKEGKAGFEQRIRDAMPLSDYFFNELSHDVDMASLDGRARLAERARPLIAKLPDGA
FRDLMAQELEKRSGARAVLQADPAAHRAMQRPTAVQRSLVRSAISLLLAQPGMADQVEKP
YRFLRLDKPGVELLAELLDLARARPGINSAMLVEHFAERPEYPSLQKLMAALAVGELEAQ
RSEFFDALARMEDQAITQRRDALTAKSREAALDPAEKTELRELLAARVRPPVASA