Protein Info for LRK55_RS05445 in Rhodanobacter denitrificans MT42

Annotation: magnesium-translocating P-type ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 848 transmembrane" amino acids 59 to 81 (23 residues), see Phobius details amino acids 87 to 109 (23 residues), see Phobius details amino acids 250 to 270 (21 residues), see Phobius details amino acids 276 to 301 (26 residues), see Phobius details amino acids 658 to 675 (18 residues), see Phobius details amino acids 720 to 742 (23 residues), see Phobius details amino acids 749 to 769 (21 residues), see Phobius details amino acids 781 to 800 (20 residues), see Phobius details amino acids 812 to 831 (20 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 18 to 81 (64 residues), 37.8 bits, see alignment 3e-13 TIGR01524: magnesium-translocating P-type ATPase" amino acids 22 to 838 (817 residues), 812.6 bits, see alignment E=3.7e-248 TIGR01494: HAD ATPase, P-type, family IC" amino acids 93 to 537 (445 residues), 152.7 bits, see alignment E=1.1e-48 amino acids 560 to 681 (122 residues), 84.7 bits, see alignment E=4.9e-28 PF00122: E1-E2_ATPase" amino acids 122 to 310 (189 residues), 148.4 bits, see alignment E=4.3e-47 PF00702: Hydrolase" amino acids 328 to 605 (278 residues), 53.2 bits, see alignment E=1.3e-17 PF13246: Cation_ATPase" amino acids 385 to 434 (50 residues), 35.3 bits, see alignment 2.4e-12 PF00689: Cation_ATPase_C" amino acids 674 to 836 (163 residues), 77.1 bits, see alignment E=3.8e-25

Best Hits

KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 54% identity to afr:AFE_2327)

Predicted SEED Role

"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.2

Use Curated BLAST to search for 3.6.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (848 amino acids)

>LRK55_RS05445 magnesium-translocating P-type ATPase (Rhodanobacter denitrificans MT42)
MNDIGAPSSPARNPVDTSLAGLFRAMESRADGLSGPEAARRLLRDGPNEARAAGRRGAIA
VLPGLFANPLVVILLLAAGVSGFLGDWAGAAIIVAIVLLSVTLNFTLSYRSQQAANRLRE
EIAPMATVRRDDRWQELPRRELVAGDVIRLSAGNRVPADARLIDARDLHVQQAALTGESA
PVEKQPADDAAGGADARQLVFLGTSVVAGTATALVYATGRRTAFGDVAETLSERPPQTEF
ERGLGDFSRLIMHTVVFLLLGVLLVGAVLHRPPLQTLLFALALAVGLTPEFMPMITAVTL
ARGAVRMARRRVIVKHLAAIEDFGSMTVLLSDKTGTLTSSETAVAATVDPFGEASTRTQL
LAQLNATFETGIRSPLDAAILRHATPATDEYRKLDEIPFDFERRRLCVVLEHGGERLLVV
KGAPESVLAACTQYEVGGAVRPLDAAATARCTQSYEAFGEQGLRVLAVAWRNVPAQDRYT
VADEAALVLAGFVTFADPLIPGVAESLRALAQDGIAVKILTGDNEKVARHVCAQVGIDVG
QLVSGTEIDALGEAALGVLAERSSVFARVSPAQKHRIVLALKARNCVVGFLGDGINDAPS
LHAADVGISVADAVDVARDAADIVLRERDLGILHAGVIEGRRAFANVMKYLLMGTSSNFG
NMFSMAAGTLFLPFLPMLPTQILLNNFLYDLAQTAIPTDHVDEAQLRRPRRWSVAVIRRF
MLGVGPISSLYDFATFYVLLHWLHASEAAFHTGWFIESLATQTLVLFVIRTAGNPLRSRP
SLPLAIGVLAALAIGIVLPWTPLAPRLGMTPLPAAFFGFLLAATATYLLLVELAKRRFMD
VGERSLQA