Protein Info for LRK55_RS05225 in Rhodanobacter denitrificans MT42

Annotation: Hsp33 family molecular chaperone HslO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 PF01430: HSP33" amino acids 8 to 278 (271 residues), 240.8 bits, see alignment E=9.8e-76

Best Hits

Swiss-Prot: 44% identical to HSLO_CHRSD: 33 kDa chaperonin (hslO) from Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)

KEGG orthology group: K04083, molecular chaperone Hsp33 (inferred from 53% identity to psu:Psesu_0747)

Predicted SEED Role

"33 kDa chaperonin (Heat shock protein 33) (HSP33)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (299 amino acids)

>LRK55_RS05225 Hsp33 family molecular chaperone HslO (Rhodanobacter denitrificans MT42)
MENLPAEDVLHRFLLERAGVRGTLLRLGPAWREVAGRVDYPPALHALLGEALAASALLTG
GIKLDGALSIELKSAGALRLLFAECSDQGRLRGLARWNEPLPAPLALDALAGAIMAITIG
NVDRGQRYQGLVDLRHADLAASLEDYFTKSEQLPARILLAADGEQAVGLMLQKMPGEGGH
AVVQDDDAWNRVVHLTATLGTQELLASAPEQLLYRLYHEESVRLFEPRPLAFGCSCSRER
VTAMLRSLGRDEVEAALAARGDEIEVVCEFCAQRYHFDRIDAEHLLSEAAAPGAPGTAQ