Protein Info for LRK55_RS05155 in Rhodanobacter denitrificans MT42

Annotation: peptide chain release factor 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 TIGR00503: peptide chain release factor 3" amino acids 3 to 527 (525 residues), 854.9 bits, see alignment E=1.9e-261 PF00009: GTP_EFTU" amino acids 10 to 276 (267 residues), 169.7 bits, see alignment E=1.1e-53 PF01926: MMR_HSR1" amino acids 14 to 141 (128 residues), 23 bits, see alignment E=1.4e-08 TIGR00231: small GTP-binding protein domain" amino acids 15 to 151 (137 residues), 70 bits, see alignment E=2.1e-23 PF03144: GTP_EFTU_D2" amino acids 312 to 378 (67 residues), 44.6 bits, see alignment E=3.3e-15 PF16658: RF3_C" amino acids 385 to 512 (128 residues), 159.5 bits, see alignment E=7.7e-51

Best Hits

Swiss-Prot: 84% identical to RF3_XANAC: Peptide chain release factor 3 (prfC) from Xanthomonas axonopodis pv. citri (strain 306)

KEGG orthology group: K02837, peptide chain release factor 3 (inferred from 84% identity to xal:XALc_2188)

Predicted SEED Role

"Peptide chain release factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (533 amino acids)

>LRK55_RS05155 peptide chain release factor 3 (Rhodanobacter denitrificans MT42)
MPTHLQETRRRRTFAIVSHPDAGKTTLTEKLLLFGGAIQMAGSVKSRKTSRSATSDWMAL
EKERGISVTSSVMQFPYEGKIVNLLDTPGHADFSEDTYRVLTAVDSALMVIDCAKGVEER
TIKLMEVCRLRDTPIMTFINKLDREGRSPIELLDEVESVLGIACAPVTWPIGMGKRLKGV
YHLALDEVHIFEQGKNFTRQDSTIFKGLDAPGLLEKIGAEAMRELREELELVQGAAPSFD
LDEYLAGRQTPVFFGSAVNNFGVQLLLDFFVEYAPSPRPRATTTREIQPEEEKLSGFVFK
IQANMDPAHRDRVAFMRVCSGTYHAGMKMIQTRTNKEVRIANALTFMASDREIVETAYPG
DVIGLHNHGTITIGDTFTEGELVTFTGIPNFAPELFRRARLRDPLKMKALQKGLAQLSEE
GATQFFRPLMSNDLILGAVGVLQFEVVAYRLKDEYNVDASFEPVTVTTARWVHCDDAKKL
EEFREKNAMNLALDAAGELVYIAPTRVNLQLAQERWPQVRFAATREHAAAVEL