Protein Info for LRK55_RS04685 in Rhodanobacter denitrificans MT42

Annotation: potassium transporter Kup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 110 to 133 (24 residues), see Phobius details amino acids 149 to 167 (19 residues), see Phobius details amino acids 179 to 199 (21 residues), see Phobius details amino acids 224 to 243 (20 residues), see Phobius details amino acids 255 to 275 (21 residues), see Phobius details amino acids 295 to 319 (25 residues), see Phobius details amino acids 348 to 368 (21 residues), see Phobius details amino acids 374 to 395 (22 residues), see Phobius details amino acids 402 to 424 (23 residues), see Phobius details amino acids 433 to 450 (18 residues), see Phobius details PF02705: K_trans" amino acids 23 to 554 (532 residues), 739.9 bits, see alignment E=7.8e-227

Best Hits

Swiss-Prot: 57% identical to KUP_THIDA: Probable potassium transport system protein kup (kup) from Thiobacillus denitrificans (strain ATCC 25259)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 57% identity to tbd:Tbd_2065)

MetaCyc: 52% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (633 amino acids)

>LRK55_RS04685 potassium transporter Kup (Rhodanobacter denitrificans MT42)
MGRQNNPIETASDARRRLRTLALGAIGVVFGDIGTSPLYTMKETLGTHGMTPTEPAVLGV
LSLVFWSLIMVVSLKYVTFVMRADNKGEGGIMALMALAQRSMSGSARARWVLAGFGIFGA
ALFYGDGVITPAISVLGAVEGLQVAAPGLGKYVVWIALAILLGMFAVQRHGTHKVGKAFA
PVMTLWFVVLAVLGVRQIIANPQVLYAINPLHAVRFFLSHGNTSFIALGGVVLALTGAEA
LYADMGHFGKKPIRLAWFGFVLPALLLNYFGQGALLLADPLAISSPFYLMVPESLLYPMI
VLSAAAAVIASQAVISGAFSMTREAMSLGYSPRLAVVHTSREMSGQIFVPWVNRMLMVLV
ILAVLGFRSSDNLGAAYGIAVTGTMTMTTLLALVVARKRWHWSWLTVVLVGVLFLIIDLS
FFGANLLKVAHGGWFPLVLGVVLFTVMTTWRRGRELVVREIKQGGLALAPFIENIAEHPP
LRVPGTAIFLTANQHAVPHALLHNLKHNKVLHERNVLLTVETLETPVAEADERIAITPMA
GNFFGLELRFGFAEDPNIPLALTQCTREGLGFDMMDTTFFLSRETIVADARRPGMALWRD
KLFAFLSRNAMPATAFFQIPGNRLIELGAQVEI