Protein Info for LRK55_RS04155 in Rhodanobacter denitrificans MT42

Annotation: SPFH domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF01145: Band_7" amino acids 23 to 204 (182 residues), 130.5 bits, see alignment E=3.7e-42

Best Hits

Swiss-Prot: 62% identical to QMCA_SHIFL: Protein QmcA (qmcA) from Shigella flexneri

KEGG orthology group: None (inferred from 74% identity to psu:Psesu_0514)

Predicted SEED Role

"Putative stomatin/prohibitin-family membrane protease subunit YbbK" in subsystem YbbK

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>LRK55_RS04155 SPFH domain-containing protein (Rhodanobacter denitrificans MT42)
MGQLLALVIVAVVVIGVAKLVRIVPQGYEWTVETFGKYTRTLSPGLHFLIPIYQAVGRKI
NMMEQVLDVPSQDVITKDNAVVRVDGVVFYQVLDAAKAAYEVANLEGAALALIMTNIRTV
LGSMDLDESLSQRDAINAKLLGVVDEATHPWGVKVNRIEIKDISPPRDLVDAMARQMKAE
REKRANILDAEGFRQAAILKAEGEKQSVILAAEGEKEAAFRAAEARERSAEAEAKATTMV
SESIANGNVNALNYFVANNYVEALKEMAKSPNQKMLLLPIEATGILGSLAGIAELAKESL
GQQQKPAAIQPPLR