Protein Info for LRK55_RS03225 in Rhodanobacter denitrificans MT42

Annotation: preprotein translocase subunit SecY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 72 to 96 (25 residues), see Phobius details amino acids 117 to 139 (23 residues), see Phobius details amino acids 152 to 173 (22 residues), see Phobius details amino acids 185 to 206 (22 residues), see Phobius details amino acids 215 to 235 (21 residues), see Phobius details amino acids 273 to 294 (22 residues), see Phobius details amino acids 315 to 338 (24 residues), see Phobius details amino acids 370 to 390 (21 residues), see Phobius details amino acids 396 to 417 (22 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 19 to 428 (410 residues), 407.6 bits, see alignment E=2.9e-126 PF00344: SecY" amino acids 73 to 415 (343 residues), 364.2 bits, see alignment E=3e-113

Best Hits

Swiss-Prot: 57% identical to SECY_PSEAE: Protein translocase subunit SecY (secY) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 65% identity to smt:Smal_0776)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (440 amino acids)

>LRK55_RS03225 preprotein translocase subunit SecY (Rhodanobacter denitrificans MT42)
MAAAKGNALGKLGKLTELRQRIFFVIGALVVFRLGSFIPVPGVNPEAMTNLVNGNGLMDM
FNMFSGGALERFSVFALGVIPYISASIVFQMMGAVVPSLQSLRKEGEAGKRKMTMYTRYA
TVALAAFQSFGIAVALQGQVAAGGAPVVYTPGFGFIFSSVVGLTAGTMFLMWLGEQMTER
GIGNGISLLIFAGIVAGLPGAVVHTLGMASNGELSLIKLLMVFALALGVTAFVVFMERAQ
RRITVNYARRSGGQKAYMNQSSNLPLKINMSGVIPPIFASSLLMFPATAVSWFSTGQQSR
WLQDLTQALSPGNPLYETVFSVLVVGFAFFYTAIVFNADETADNLKRSGALIPGIRPGKA
TAGYIDAVMTRLTGVGALYLVLVCLVPSFMQSAWHVPFYFGGTSLLIVVVVVMDFTAQVQ
AHLVSHQYESLLKKANLRRS