Protein Info for LRK55_RS01975 in Rhodanobacter denitrificans MT42

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 423 to 443 (21 residues), see Phobius details PF13424: TPR_12" amino acids 187 to 252 (66 residues), 30.5 bits, see alignment E=3.5e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 452 to 616 (165 residues), 156.8 bits, see alignment E=2e-50 PF00990: GGDEF" amino acids 456 to 613 (158 residues), 146.8 bits, see alignment E=5.1e-47

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (618 amino acids)

>LRK55_RS01975 GGDEF domain-containing protein (Rhodanobacter denitrificans MT42)
MLLLAATPCAFAAPPPAHDAAAFDLLVRQLDNGDIPLNSQAAARQALDRLGALLPPGDAY
RQRRYDYLYCFLAFDNDVKGGYAYAGRGTEQAQQAGDLEAESNFRICRGLYQSKLTTERD
ALPDYEAGIRLARRLENPRLIADALTWRGSAQSLLGEQAKALFDFLEAQRLYETVGNTTA
AQSNLISIATIYRRLGEYDKAGEYLRQSMQSAQRKGDKQEQMVVDMQLGFLATERGDPVG
AVAPLQRALALAHETGSRQSVGSALLALAESSNARERYAEALQQVEAAAKEFQAVADQSN
VGMLALQSAKAHAGLGQHELAAREFDLAEASVRNSRNMRYLAELYDARSRNQEALGKPAA
ALADLRLKMEADAALARMAKTQLTTLMSYQFDTERRELENRKLAADKALKEQQLATLERV
RGWQWLAILLAGLLLLLMLWLAWRQLRQSRRLHRLALTDALTGISNRRHIEHTLHGAVEH
ARRGQRELAVIMLDIDHFKRVNDSHGHPAGDQALEQLVHACLGALRQHDRLGRLGGEEFL
VVLPDTDLEGGLQVAERLRACVAAARPLVNGVELQLSISLGVAQLRPAESGAASLVRRAD
AALYHAKDNGRNRVEAAP