Protein Info for LRK55_RS00820 in Rhodanobacter denitrificans MT42

Annotation: translation initiation factor IF-2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 933 PF04760: IF2_N" amino acids 1 to 47 (47 residues), 25.7 bits, see alignment 2.7e-09 amino acids 359 to 405 (47 residues), 54.2 bits, see alignment 3.4e-18 PF08364: IF2_assoc" amino acids 68 to 111 (44 residues), 51.7 bits, see alignment 2.8e-17 TIGR00487: translation initiation factor IF-2" amino acids 349 to 933 (585 residues), 820.5 bits, see alignment E=9.3e-251 TIGR00231: small GTP-binding protein domain" amino acids 435 to 592 (158 residues), 103.8 bits, see alignment E=8.2e-34 PF00009: GTP_EFTU" amino acids 437 to 593 (157 residues), 124.9 bits, see alignment E=1e-39 PF01926: MMR_HSR1" amino acids 438 to 543 (106 residues), 40.4 bits, see alignment E=1e-13 PF00071: Ras" amino acids 439 to 593 (155 residues), 23 bits, see alignment E=1.8e-08 PF11987: IF-2" amino acids 712 to 822 (111 residues), 128.1 bits, see alignment E=5.7e-41

Best Hits

Predicted SEED Role

"Translation initiation factor 2" in subsystem NusA-TFII Cluster or Translation initiation factors eukaryotic and archaeal or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (933 amino acids)

>LRK55_RS00820 translation initiation factor IF-2 (Rhodanobacter denitrificans MT42)
MSDVTIKQLAQVLGMPVDKLLTQLGEAGMKFSDQEQVISSTEKVKLLGFLRRTHGKSEAA
AEVDDSAPRQITLKRRTVGELKVAAPGGRGATGAAKTVNVEVRAKRTYVKRSVIAEEASA
EPEREDAVRKLQESQQQREQEERERTEAEQRRQAEAQHALDEQRRRAEKEQHEVEPAGPV
EPAVVEHVEATPEPAAEAAPVAAGDDAAAAVQRIDQRDLGMILPRIHEPRKREKPVKPAA
APAAPVAPAARAVVAGGAVASTAAGDAGRGKPKHPRERNDSVGSKEDRDAGKRFAGGQMH
LSEADRARRSSSSKRGKPGRSGGREPLRGGGAGPTGPHGFSRPTAPVVREVVVGDTNVVA
ELAQKMAVKGSEVVKALFKMGVMATINQTVDHDTAVLVVEELGHTPVADNQNNAEETLAA
HTQTIELEGEKVSRPPVVTIMGHVDHGKTSLLDYIRRTKVASGEAGGITQHIGAYHVQTS
KGVITFLDTPGHAAFTSMRARGAQSTDIVILVVAADDGVKPQTIEAVKHARAAKVPLIVA
VNKMDKDGANPDNVKQGLVAQEVVPEDWGGDVQFVPVSAKTGMGVEDLLDAISVQAEVME
LKAVVDGRASGVVIESSLDRGRGPVATVLVQQGTLRKGDFVVCGVEYGRMRALIDETGKQ
VAEAGPSIPVQVLGLSGVPETGDDFVAVEDERLAREVAEERQLKRRETRMVSKSNRLEDI
IAKMGQGEEQQTLNILVKGDVQGSVEALRESLTQIGNDRVRVNVVASGVGGITESDATLA
AASKALVIGFNVRADASARKVIETNGLDVRYFSIIYDVIDQVTQAATGLLGMEVREDIIG
TAEVRDVFRSSKFGAVAGCMVTEGVVKRSKPIRVLRDHVVIFEGELESLRRFKDLVDEVR
NGMECGIAVKQYNDVKPGDQIECFERTEVARTL