Protein Info for LRK55_RS00550 in Rhodanobacter denitrificans MT42

Annotation: translational GTPase TypA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 608 PF00009: GTP_EFTU" amino acids 5 to 196 (192 residues), 188.7 bits, see alignment E=2.1e-59 TIGR00231: small GTP-binding protein domain" amino acids 5 to 155 (151 residues), 85 bits, see alignment E=4.9e-28 TIGR01394: GTP-binding protein TypA/BipA" amino acids 6 to 604 (599 residues), 922.2 bits, see alignment E=1.1e-281 PF01926: MMR_HSR1" amino acids 9 to 130 (122 residues), 22.4 bits, see alignment E=2.9e-08 PF03144: GTP_EFTU_D2" amino acids 220 to 290 (71 residues), 48.4 bits, see alignment E=2.5e-16 PF00679: EFG_C" amino acids 401 to 481 (81 residues), 79.5 bits, see alignment E=3.9e-26 PF21018: BipA_C" amino acids 490 to 598 (109 residues), 145.1 bits, see alignment E=1.7e-46

Best Hits

Swiss-Prot: 69% identical to TYPA_ECOLI: GTP-binding protein TypA/BipA (typA) from Escherichia coli (strain K12)

KEGG orthology group: K06207, GTP-binding protein (inferred from 90% identity to xcb:XC_3309)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (608 amino acids)

>LRK55_RS00550 translational GTPase TypA (Rhodanobacter denitrificans MT42)
MSIEKLRNIAIVAHVDHGKTTLVDCLLKQSGTLSERTVLAERVMDSNDQEKERGITILAK
NTAITWQGNRINIVDTPGHADFGGEVERVLSMVDSVLILVDAMDGPMPQTRFVTQKAFAM
GFKPIVVINKVDRPGARPEWVVEQVWDLFDRLGATPEQMDFPIVYASALNGYASLDDSVR
EGDMTPLYEAIMRHVSKPDVDPDGPFQMRISQLDYNNFVGVIGIGRIQRGTLKKNMPVAV
IDRHGKKRQGKVLQVLGFMGLERIEQETAEAGDIVAISGIADLTISDTICALDTPEALPA
LTVDEPTISMTFQVNNSPFAGNKDLSGGKFLTSRQLKDRLEREQVHNVALKVEQGSDADK
FLVSGRGELHLSVLIENMRREGYELAVSRPEVIIKEIDGQKMEPIEQLVVDVEETHQGPV
MERLGMRKGQLKNMEPDGKGRVRLEYMIPARGLIGFQNQFKTLTQGSGLLFHVFDHYGPK
EEGQIAKRLNGVMIANAGGTTPAYSLGPLQDRGKLFAAEGDNVYEGQLVGIHAKDNDLTV
NVIKPKPLTNMRASGKDDAIQLTPAIKFTLEQALDFIDDDELVEVTPKEIRLRKKHLTEN
DRKRASRG