Protein Info for LRK54_RS17535 in Rhodanobacter denitrificans FW104-10B01

Annotation: cation transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 52 to 70 (19 residues), see Phobius details amino acids 79 to 100 (22 residues), see Phobius details amino acids 108 to 128 (21 residues), see Phobius details amino acids 149 to 166 (18 residues), see Phobius details amino acids 172 to 190 (19 residues), see Phobius details PF01545: Cation_efflux" amino acids 19 to 193 (175 residues), 65.4 bits, see alignment E=3e-22

Best Hits

KEGG orthology group: None (inferred from 60% identity to mpt:Mpe_A2355)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcD" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (207 amino acids)

>LRK54_RS17535 cation transporter (Rhodanobacter denitrificans FW104-10B01)
MSDCGCHAEAASEAERRILRIALGLNATMFVVGVVAGLIAQSMGLVADSLDMLGDACAYG
IALLAWTRSAYFKASAAHWNGTLLVVLGVGVLVGVLWRLVTGSHPEGLWMMSVAFVSLIV
NATVLRLLARFRHGEVHLRAIWICTRADVIANLAVIVSGVLVLLLHSAVPDLVIGTAIAC
YVLKEALGILREAKDARIAAIAPNGKP