Protein Info for LRK54_RS17125 in Rhodanobacter denitrificans FW104-10B01

Annotation: ABC transporter transmembrane domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 590 transmembrane" amino acids 31 to 53 (23 residues), see Phobius details amino acids 73 to 97 (25 residues), see Phobius details amino acids 142 to 166 (25 residues), see Phobius details amino acids 172 to 191 (20 residues), see Phobius details amino acids 254 to 274 (21 residues), see Phobius details amino acids 285 to 306 (22 residues), see Phobius details TIGR02204: ABC transporter, permease/ATP-binding protein" amino acids 14 to 588 (575 residues), 824.9 bits, see alignment E=2e-252 PF00664: ABC_membrane" amino acids 35 to 297 (263 residues), 163.4 bits, see alignment E=9.5e-52 PF00005: ABC_tran" amino acids 368 to 517 (150 residues), 114.3 bits, see alignment E=7.1e-37

Best Hits

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 62% identity to psu:Psesu_1339)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (590 amino acids)

>LRK54_RS17125 ABC transporter transmembrane domain-containing protein (Rhodanobacter denitrificans FW104-10B01)
MSDAPTDTSRPAHRIGALRELWPFLKPHRALALGWLLFLALSSGASLVLPLAFRHIIDQG
FGHSSNTVINQTFVALFGVALVLAFATAARYFCITLLSERALASLRQTLYAHVIRLDVGF
FEKSRVGELLSRLSADTEVVQALIGSGVSVALRSAVMLVGAAVAMVWTAPSLAGLTALVI
PAVMLPILLFGRRVQKLSRASQDRLADAAAIANETLNASTAVKAYAREDIESTRYGGAIT
RALATARRRIGMRALLTMAVIVLVFGAITLVLWAGARHVLAGTLGAGVLGQFVLYAVFAA
GSVAGLSEVWGDVLRAAGAMERIGELLGERADIVDPAQPQVLPQPMRGELRFDGVTFHYP
TRPDAAALHDFTLTVRPGETVALVGPSGAGKSTVFALLLRFYDPQSGSIRIDGIDLRETT
LAGLRGAIALVPQETVIFAGSAADNIRFGRQDAGDDEVRDAALAAEAHEFISALEHGYDA
ELGERGVRLSGGQRQRIAIARAILRDAPLLLLDEATSSLDAQSEAAIQQALARLEQGRTT
LVIAHRLATVQRADRIVVMDGGRIVAQGTHESLLAEGGLYAELARLQFVA