Protein Info for LRK54_RS15610 in Rhodanobacter denitrificans FW104-10B01

Annotation: D-serine/D-alanine/glycine transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 44 to 66 (23 residues), see Phobius details amino acids 95 to 120 (26 residues), see Phobius details amino acids 127 to 146 (20 residues), see Phobius details amino acids 156 to 179 (24 residues), see Phobius details amino acids 203 to 224 (22 residues), see Phobius details amino acids 244 to 266 (23 residues), see Phobius details amino acids 278 to 299 (22 residues), see Phobius details amino acids 335 to 357 (23 residues), see Phobius details amino acids 363 to 388 (26 residues), see Phobius details amino acids 408 to 428 (21 residues), see Phobius details amino acids 434 to 451 (18 residues), see Phobius details PF00324: AA_permease" amino acids 19 to 458 (440 residues), 408.4 bits, see alignment E=3.9e-126 PF13520: AA_permease_2" amino acids 22 to 445 (424 residues), 142.9 bits, see alignment E=1.4e-45

Best Hits

Swiss-Prot: 72% identical to CYCA_ECOL6: D-serine/D-alanine/glycine transporter (cycA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K11737, D-serine/D-alanine/glycine transporter (inferred from 86% identity to xcv:XCV0656)

MetaCyc: 72% identical to D-serine/alanine/glycine:H+symporter (Escherichia coli K-12 substr. MG1655)
RXN0-5130; RXN0-5201; RXN0-5202; RXN0-5203; TRANS-RXN-62A; TRANS-RXN-62B

Predicted SEED Role

"D-serine/D-alanine/glycine transporter" in subsystem Glycine and Serine Utilization or Pyruvate Alanine Serine Interconversions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>LRK54_RS15610 D-serine/D-alanine/glycine transporter (Rhodanobacter denitrificans FW104-10B01)
MTASLEHPEHLRRSLSNRHLQLIAIGGAIGTGLFMGSGKTISLAGPSILLVYLIIGVMLF
FVMRAMGELLLSNLEYKSFIDFSTDLLGPWAGFFCGWTYWFCWVITAIADVIAIAAYAQF
WFPGLAPWIPAVLCVLLLLSLNLVTVKLFGELEFWFALIKIVAIVALIATGFALVAWGFT
SPSGHKASLANLWSDGGFFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETADPKRNLPKA
INSIPVRIIIFYVLALIAIMVVTPWRLVEAGKSPFVELFVLAGIPAAASLINFVVLTSAT
SSANSGIFSTSRMLYGLAEEQHAPKTFARLSRAAVPSLGLLFSCFCLLLGAAMIYLIPDL
ITAFTLITTLSAVLFMFVWSLILFGYIAYRRQRPQLHQASIYKMPGGVFMCWACLAFFVF
VLVLLSLQPDTREALIASPVWFVLLGIGYLWKGRRARRGVALPAE