Protein Info for LRK54_RS14895 in Rhodanobacter denitrificans FW104-10B01

Annotation: nicotinamide riboside transporter PnuC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 195 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details transmembrane" amino acids 25 to 43 (19 residues), see Phobius details amino acids 49 to 67 (19 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 112 to 131 (20 residues), see Phobius details amino acids 137 to 154 (18 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details PF04973: NMN_transporter" amino acids 4 to 181 (178 residues), 174.5 bits, see alignment E=1e-55 TIGR01528: nicotinamide mononucleotide transporter PnuC" amino acids 4 to 184 (181 residues), 68.5 bits, see alignment E=3.6e-23

Best Hits

KEGG orthology group: K03811, nicotinamide mononucleotide transporter (inferred from 58% identity to smt:Smal_0149)

Predicted SEED Role

"Ribosyl nicotinamide transporter, PnuC-like" in subsystem NAD and NADP cofactor biosynthesis global or NAD regulation or PnuC-like transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (195 amino acids)

>LRK54_RS14895 nicotinamide riboside transporter PnuC (Rhodanobacter denitrificans FW104-10B01)
MVRIELAAALVSAWAVWLTTRRRPWCWPVGLVSVLVYAWVFVHAKLYSDALLQLAFALLI
GYGWWRWLQHMGGDGRVEVAALPRRQAVAHLAIGGLGALALGAFMHYRTDAALPWLDAAL
TAFSLVAQWWQAKRHVASWWLWIAVDVIYVGEYVYKHLLITSVLYAGFVLLAVLGLRAWR
RVAKTAAPHQPGTAY