Protein Info for LRK54_RS13700 in Rhodanobacter denitrificans FW104-10B01

Annotation: magnesium and cobalt transport protein CorA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 transmembrane" amino acids 281 to 300 (20 residues), see Phobius details amino acids 312 to 332 (21 residues), see Phobius details PF01544: CorA" amino acids 48 to 334 (287 residues), 214.8 bits, see alignment E=8.6e-68

Best Hits

KEGG orthology group: K03284, metal ion transporter, MIT family (inferred from 58% identity to sml:Smlt1589)

Predicted SEED Role

"Magnesium and cobalt transport protein CorA" in subsystem Campylobacter Iron Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (338 amino acids)

>LRK54_RS13700 magnesium and cobalt transport protein CorA (Rhodanobacter denitrificans FW104-10B01)
MNPITPPSAPPSSSPPMVVNCIAYRRDGSRIGEVTIDAISDVLAEPDTFVWVGLYEPDET
LLEKIQDEFGLHDLAIEDAHAAHQRTKLETYGDSLFLVVQTAQLVDGELAFGETHIFFGP
RYLVTVRHGASQSYAPARRTCEHAPELLANGPSYGLYGVLDFIVDNLLPIVRDFREEVHQ
LEHDIFGETFKSSTVRRLYDMQRDLMTLRLAVAPLQDIINQLIRLHPHLIPEVLHAYFRD
VYDHAFRVNEAIGAMREMLTAAINVNLSLVSLRQNEVMKKLAGWAAMLAAPTLLTSWYGM
NFAHMPELGQPWAYPAIIVVMACVVGGIYLGLKRARWL