Protein Info for LRK54_RS13660 in Rhodanobacter denitrificans FW104-10B01

Annotation: protein-glutamate O-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 PF03705: CheR_N" amino acids 25 to 77 (53 residues), 69.5 bits, see alignment 1.5e-23 PF01739: CheR" amino acids 91 to 290 (200 residues), 204.7 bits, see alignment E=1e-64

Best Hits

KEGG orthology group: K00575, chemotaxis protein methyltransferase CheR [EC: 2.1.1.80] (inferred from 48% identity to tcx:Tcr_0757)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (294 amino acids)

>LRK54_RS13660 protein-glutamate O-methyltransferase (Rhodanobacter denitrificans FW104-10B01)
MRAAAGMVQGDAVPADGGGVALGDAEFRFLRDFVYEHCGIALGEHKRQLVQGRLARRLRA
LGLRHFGAYCELLRHDPQSELDNLASVISTNVTSFFREQHHYDLLVDELLPQWLQQKRRS
GDRLRIWSAGCSTGEEPYALAMVLAEALERHGAAGIDAKILATDLSPQALETARNGVYPL
ERLAGISDERRCRWMLRGAGEYEGFACVHPRLRELVTVQPLNLLHEWPMRGPFDAIFCRN
VVIYFDQPTKQRLFRRYAALLPAGGHLFLGHSESLHGINDDFELIGRTVYRKLG