Protein Info for LRK54_RS13485 in Rhodanobacter denitrificans FW104-10B01

Annotation: sigma-54-dependent Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 PF06490: FleQ" amino acids 7 to 116 (110 residues), 33.8 bits, see alignment E=1.1e-11 PF14532: Sigma54_activ_2" amino acids 133 to 303 (171 residues), 79.7 bits, see alignment E=7.7e-26 PF00158: Sigma54_activat" amino acids 133 to 298 (166 residues), 244.3 bits, see alignment E=1.7e-76 PF07728: AAA_5" amino acids 156 to 276 (121 residues), 32.7 bits, see alignment E=2.1e-11 PF02954: HTH_8" amino acids 426 to 466 (41 residues), 45.3 bits, see alignment 1.8e-15

Best Hits

Predicted SEED Role

"Flagellar regulatory protein FleQ" in subsystem Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (474 amino acids)

>LRK54_RS13485 sigma-54-dependent Fis family transcriptional regulator (Rhodanobacter denitrificans FW104-10B01)
MQKFDFLVIESDEARVDFVLSALHFLGYRPQHGAACGEVDESTHAWRAVYIGSVADAAEA
ERQFALLGAAVSHVPVLLAGDSPWVERFSTASSPFAARMATLEFPLRYEKMAEAMRNIYA
RLLGGQSGALRFVGNSAPMIRVNGLIRQVAPFDSTVLVLGESGTGKEMVARAIHEHSPRR
DKPFVAINCGAIPAELLESELFGHEKGSFTGAISARKGRFEMAEGGTLFLDEVGDMSLPM
QVKLLRVLQERAYERVGGSKTLRCDVRIIAATHRNLEESIASDRFREDLFYRLSVFPLEL
PSLRERLDDLPVLIGEFNQRLARRGLGVVRFSAGAMQALREHAWPGNVRELSNLVERMAI
LFPHGEVRGSDLPKKYRGQQAVDEVHGAALLALMDDELPPCEAGVHPVAEALRTLPEQGL
DLKDHLADIEVGLIRQALDVTGGVVAHAARLLHMQRTTLVEKLRKYGLQNSLAA