Protein Info for LRK54_RS12235 in Rhodanobacter denitrificans FW104-10B01

Annotation: putative lipid II flippase FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 transmembrane" amino acids 21 to 45 (25 residues), see Phobius details amino acids 54 to 75 (22 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 119 to 143 (25 residues), see Phobius details amino acids 153 to 171 (19 residues), see Phobius details amino acids 176 to 193 (18 residues), see Phobius details amino acids 198 to 217 (20 residues), see Phobius details amino acids 285 to 306 (22 residues), see Phobius details amino acids 318 to 342 (25 residues), see Phobius details amino acids 354 to 375 (22 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 21 to 378 (358 residues), 403.4 bits, see alignment E=4.3e-125 PF01098: FTSW_RODA_SPOVE" amino acids 24 to 376 (353 residues), 320.2 bits, see alignment E=8.4e-100

Best Hits

Swiss-Prot: 54% identical to FTSW_XANOR: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 55% identity to psu:Psesu_0638)

MetaCyc: 43% identical to peptidoglycan glycosyltransferase FtsW (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>LRK54_RS12235 putative lipid II flippase FtsW (Rhodanobacter denitrificans FW104-10B01)
MPIFDATSQAKRRSGPRGSFDLWLLVALVGLASVGVVMVTSSSIAVADSQHLGAFYFLKK
HLLFLGLGLFAAGLAMRTELKLLEKYAFPLLALAFLMLLAVFVPHLGMRINGARRWLNLL
VTTFQPVEAVKLILVVYVASYLVRHRENVETKFLGLFKPVLVAGMIVLLLLAQPDFGSAT
LVIAVTIAMVWLGGARPIFLFLMGLPLMPLLYVAATGESYRMKRLTSFMDPWKDPFNDGF
QLTQSLMAIGRGEWTGVGLGSSVLKLSYLPEAHTDFIFAVIGEELGLAGVLLVIGLFGLA
VGRGLYLGLKGVEVGQRFAGYVAFGVSLMLAMQAFVSVGVNLGALPTKGLTLPLISYGGS
SMVLTCAMAGVLLRATWEINRALDARQMATRMPAAVAVADANVAAKPREAVAA