Protein Info for LRK54_RS12015 in Rhodanobacter denitrificans FW104-10B01

Annotation: HAMP domain-containing histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 137 to 159 (23 residues), see Phobius details PF00672: HAMP" amino acids 158 to 210 (53 residues), 23.2 bits, see alignment 1.1e-08 PF00512: HisKA" amino acids 217 to 279 (63 residues), 60.5 bits, see alignment E=1.9e-20 PF02518: HATPase_c" amino acids 331 to 415 (85 residues), 67.9 bits, see alignment E=1.6e-22

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (427 amino acids)

>LRK54_RS12015 HAMP domain-containing histidine kinase (Rhodanobacter denitrificans FW104-10B01)
MQSRRKLRFRLIVSFALFGFGLSALFAFAALNIRTRVEDQLVNASLMDDAKWANQQAREH
PGAPSGSRLLTGTVLSDRTLYKAPLTWQSLENGVHDIFEPGPDGEEHHYKLAVYREGGII
SFLQYDVSREELGKQQLLFSVIGAVFLFGLLSLAIGLWLSRKVLKPVSELANRLRDFRKA
GKAEPLAPHFADDEVGELAHALDEYSARLTAMVERDREFNSDVSHELRTPLAVIASTTEL
LQGSPDLTEKLSERLKRIERASRQATELIEALLLLSRAERRGPTRGETTEVGKVAADVIE
SQRPQMRGKPLSIELAVNAPVSVNAPASVLSVALTNLIGNAIKYTLEGSVRVEVGDGRIE
VIDTGPGIKPEDAERLFQRGVRGEGAGGSGAGLGLAIVRRLCELYGWDVSMRPRTDANGA
IASIRFS