Protein Info for LRK54_RS11880 in Rhodanobacter denitrificans FW104-10B01

Annotation: VWA domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 310 to 336 (27 residues), see Phobius details PF13519: VWA_2" amino acids 100 to 203 (104 residues), 27.7 bits, see alignment E=5.6e-10 PF07719: TPR_2" amino acids 405 to 437 (33 residues), 30.1 bits, see alignment (E = 4.8e-11) PF00515: TPR_1" amino acids 406 to 437 (32 residues), 32.5 bits, see alignment (E = 8.1e-12)

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 33% identity to vpa:VPA1455)

Predicted SEED Role

"TPR domain protein in aerotolerance operon"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (627 amino acids)

>LRK54_RS11880 VWA domain-containing protein (Rhodanobacter denitrificans FW104-10B01)
MSELLQQFHFLRPWWLAALLLLPPLGWLGVRRNVAQVELSRLVDAELLPHLLRGRAGNRS
LPLWLFALGWTLCALALAGPTWSRVEQPLYASRAAQVVAISLSQRMLARDVAPSRLDRTR
YKARDLLHANQDGLNALVGYAGEAFVVAPLTSDAHSLDDLLEAMAPDTMPVDGDNAAAAI
ERGVALIQGGKVSGGSLVLITDQADAAAAAAARKANATGVRVSVLGVGTPQGGPVPLPDG
GFVRDAQGGMLLARRDDAALAALAAAGGGRYVAMSADQRDVDALHAQLRSAKATLADGQV
GDAWQDRGAWLLLPLLLVVALAFRRGWLLLLPLVVLPLWPGAAEATTWHDLWQRRDQQAA
QALHAGDAKQAQQLARDPAWRGAAAYRAGDYAAAAQALQQAPGGDAAYNLGNTLAKQGAY
QKALAAYDHALQLDPANADAKANRQAVEDWLRQQQQPSDQKEHEGHGGKQNQSSQGEQGK
SGKQDAKDQSSAANDAEPSDQPGRDGKSQAQDQSGKNASQQGKSEQGGADQPKPQTTQQQ
AEQQAQAEQAQQALKQQMDAALAKPGESKAEHQLGALAKDDPQAKLPADLRHALQRVPDD
PGALLRRKFELEYQQRHGGAPSEDGQP