Protein Info for LRK54_RS11875 in Rhodanobacter denitrificans FW104-10B01

Annotation: VWA domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 55 to 73 (19 residues), see Phobius details amino acids 132 to 148 (17 residues), see Phobius details amino acids 299 to 317 (19 residues), see Phobius details PF13519: VWA_2" amino acids 87 to 198 (112 residues), 59.2 bits, see alignment E=8.7e-20 PF00092: VWA" amino acids 88 to 277 (190 residues), 65.5 bits, see alignment E=1.1e-21

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 51% identity to xal:XALc_2345)

Predicted SEED Role

"BatA (Bacteroides aerotolerance operon)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (328 amino acids)

>LRK54_RS11875 VWA domain-containing protein (Rhodanobacter denitrificans FW104-10B01)
MAEFAWPWVIVLLPLPWLLRRWLRPAAPGQALHLPQPGVRLATVASSRAHGTTPWLLALA
WLCLLAAAARPQWVGPPQAQQRSGRALLLAVDLSGSMRTGDMQLAGQDVSRFGAVEAIAG
DFISRRSGDEMGLILFGSQAFLVTPLTYDLSAVRAQLQGAAVGLAGTETAIGDAIAVAVK
RLAALPEQARVLVLLTDGVNNAGSIAPRDAARAAKAAGVRIYTIGIGATRMRIPGFFGSQ
LVNPSADLDADMLTDIATQTGGRFFRATDSGELADAYRAIDALEPMPQHGPSLRPRHELF
RWPLLAAIALLLLVIVPRRFTRTRRLLA