Protein Info for LRK54_RS11600 in Rhodanobacter denitrificans FW104-10B01

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 216 PF00072: Response_reg" amino acids 8 to 120 (113 residues), 100.8 bits, see alignment E=7.6e-33 PF08281: Sigma70_r4_2" amino acids 154 to 196 (43 residues), 34.9 bits, see alignment 1.5e-12 PF00196: GerE" amino acids 154 to 209 (56 residues), 68.5 bits, see alignment E=4.4e-23

Best Hits

Swiss-Prot: 37% identical to NREC_STAHJ: Oxygen regulatory protein NreC (nreC) from Staphylococcus haemolyticus (strain JCSC1435)

KEGG orthology group: None (inferred from 53% identity to kko:Kkor_1204)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (216 amino acids)

>LRK54_RS11600 response regulator transcription factor (Rhodanobacter denitrificans FW104-10B01)
MPPKPIRVLLVDDHNLVRESLVGILQSDGDIEVIAQAADGVEAIGKALATRPDIVITDLS
MPRLNGIELVRRLNQELPGTRVLVLTMHQEDQYVLQAVRVGASGYLVKDSAAAELLAAVR
NVHAGRGHFGPHASRALAEQLQHPERLPDDRYELLTAREREVFRLIAEGLTTKEIARRLS
ISTKTAENHRTRVLTKIAVRNTAELVRYALRRGLLD