Protein Info for LRK54_RS10865 in Rhodanobacter denitrificans FW104-10B01

Annotation: DEAD/DEAH box helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1005 PF04851: ResIII" amino acids 539 to 695 (157 residues), 26.6 bits, see alignment E=7.6e-10 PF00176: SNF2-rel_dom" amino acids 544 to 824 (281 residues), 231.4 bits, see alignment E=1.9e-72 PF00271: Helicase_C" amino acids 838 to 947 (110 residues), 78.9 bits, see alignment E=5.2e-26

Best Hits

Predicted SEED Role

"COG0553: Superfamily II DNA/RNA helicases, SNF2 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1005 amino acids)

>LRK54_RS10865 DEAD/DEAH box helicase (Rhodanobacter denitrificans FW104-10B01)
MQQPDGKQHAAATPSGEDEALPQAWRRLLAAPKPAVADEHGVLGFFLEVMPEEGAAFARL
DVAPVLLAVAEHGRYARPVPLDSRHLAQSPLPPHEQRLAATMLGLPQSVRKGRSYARLGG
HVGDTLLAEILDTAPCFLGGLAGLRLSRGKSHPLNWHWQLEPDGSQRLLPVLPHSQRLLR
IDGLWCLDAERATVGRFDAAVEETRWLELPPLKHEHGRRLRNRLAGSRLATRVPLPLVFD
EVRRSALAPKPVLTLHALTRHVRLAAGTPPLGYARLAFDYAGERLPARGGEPLVRRVRNG
QLVEITRRRAEELSAMEQLERAGLTPGVDTEGLPWDVAETLPDDAWLFPGTGYAGALEVN
TPARWLALRPKLEAENFQVEYAPSFPFEVLEGPVHWYGQAVEDADDHAFDLEIGIELDGE
RHNLLPAVAQALAEHQLNLRPAPNEPEDAVWYAPVDARRRVPVRLKELRGLLAPLAEYLE
KPRQKLHLPRVQAGRLEELVAAMPGGSTLEAAEPLLGFAARLRDAAERASDAVPDGLTVE
LRPYQREGLRWLNALAEAGVGGVLADDMGLGKTLQLITHLLSLKQGGALTQPALIVVPTS
LIPNWQSEIARFAPMLHVLTLHGPQRAEEFAQLGAQDIVLTSYALLPRDVVALRKQPFAL
IVLDEAQQVKNPRTQARRALLSLRTPRYVCLTGTPLENHLGELWSQVDLAVPGLLGDESA
FRRFYRIPIEKQHDEECQQRLNLRIAPFILRRSKAQVAKELPPKTEITRRVVLEGRQRDL
YEGLRLSLAEELREVIAQRGIAHSGIVVLDALLKLRQVCCDPRLVKLEAARGVHESAKFE
LLMDMLPALLDEGRKVLLFSQFTGMLKLIAAELDRRRIRYVTLTGDTRDRAEPVQRFQNG
EVPLFLLSLKAGGVGLNLTAADTVIHYDPWWNPAAEAQASDRAHRIGQDKPVFVFRLITS
GTVEERIEQLKERKAELAAAVLEGGGSREKLSFDEGDLDTLLAPG