Protein Info for LRK54_RS09960 in Rhodanobacter denitrificans FW104-10B01

Annotation: type II secretion system ATPase GspE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 PF05157: MshEN" amino acids 57 to 163 (107 residues), 65.7 bits, see alignment E=4.1e-22 TIGR02533: type II secretion system protein E" amino acids 96 to 574 (479 residues), 679.8 bits, see alignment E=1e-208 PF00437: T2SSE" amino acids 200 to 466 (267 residues), 357.9 bits, see alignment E=3e-111

Best Hits

Swiss-Prot: 70% identical to GSPE_XANCP: Type II secretion system protein E (xpsE) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K02454, general secretion pathway protein E (inferred from 72% identity to sml:Smlt0687)

Predicted SEED Role

"General secretion pathway protein E"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>LRK54_RS09960 type II secretion system ATPase GspE (Rhodanobacter denitrificans FW104-10B01)
MSAAIEPAVGGSGQVADDRETEVCAWLVARGRLKDSDLGRARRLHEESAEGTLTTLMARL
GLVSERDLAEAWADLLQVPLLAARDAPELPPADLEVSLRFLKQQHVVPVQDDQHGLALIV
ADPADPYPLQAVELAAGRPVALRVGLRSEIDGLIERYYGSGRSAMGTIVENLDGSAAEED
DVEHLRDLASEAPVIRLVNLILQRAVEQRASDVHIEPFENRLKVRYRIDGVLHEVEAPPS
SSTAAVISRVKIMARLNIAERRLPQDGRIQLRVQGKELDLRVSTVPTSFGESVVMRILDR
ESVVFDFASLGFTDSFQQRFVDVLEKPHGILLVTGPTGSGKTTTLYTALSRINTNDVKII
TVEDPVEYQLEGINQIQVKPQIGLDFSGALRSIMRQDPDVIMIGEMRDLETCRIAIQSAL
TGHLVLSTLHTNSAAGGITRLLDMGVEDYLLGSTINGILAQRLVRRLDPETAIPYEALPE
VIEQFELHKYTDERPIRLWRPGSSAANPSGYRGRRAIMEFLTMSDPLRRLVMQRANEGDI
EKQARAEGMRTMYEDGIAKAVAGITTLEEVLRVTQEG