Protein Info for LRK54_RS09285 in Rhodanobacter denitrificans FW104-10B01

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07690: MFS_1
  • amino acids 17 to 383 (367 residues), 61.8 bits, E=8.2e-21
• PF05977: MFS_3
  • amino acids 61 to 333 (273 residues), 37.6 bits, E=1.5e-13
• PF01553: Acyltransferase
  • amino acids 438 to 566 (129 residues), 85.6 bits, E=4.1e-28

Best Hits

KEGG orthology group: None (inferred from 58% identity to xal:XALc_0304)

Predicted SEED Role

"1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria or Phosphate metabolism (EC 2.3.1.51)

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• oleate biosynthesis III (cyanobacteria) (2/3 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (9/13 steps found)
• palmitoleate biosynthesis III (cyanobacteria) (1/2 steps found)
• phospholipid remodeling (phosphatidate, yeast) (1/2 steps found)
• CDP-diacylglycerol biosynthesis III (3/5 steps found)
• phosphatidate biosynthesis (yeast) (3/5 steps found)
• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• palmitoyl ethanolamide biosynthesis (2/6 steps found)
• superpathway of stearidonate biosynthesis (cyanobacteria) (2/6 steps found)
• stigma estolide biosynthesis (2/7 steps found)
• anandamide biosynthesis II (2/8 steps found)
• anandamide biosynthesis I (3/12 steps found)
• plasmalogen biosynthesis I (aerobic) (2/16 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.51

Use Curated BLAST to search for 2.3.1.51

Protein Sequence (624 amino acids)

>LRK54_RS09285 MFS transporter (Rhodanobacter denitrificans FW104-10B01)
MSQFALLGKRRFAPFFWTQALGAFNDNAFRNALVMLVAFQMGLGDRTVSLYTNLAPALFI
IPFFLFSATAGQLAEKYEKSRIIRYVKLFEIGAMALAAYGFYTHHTTLLLIVLFMMGMHS
TMFGPIKYAILPQALKPAELVGGNGLVEMGTQMAMLVGMIAGNSLMLVAGVGPLLASGAT
IAVAVAGYLASRRIPPAPATAPELKFNWNPFSETARVLAITRADRPVFNAVLGISWFWFF
GTVLIAQLPIYTRETLGGDGSVNTLVLTLFSIGTGLGALLCEKLSGRRVEIGLVPLGAFG
LTAFGVELYFARHGMVAVRGLDWLAFLQAAGSWRVVLDLTLIGVFAGLYVVPLFAYVQAR
APREKLSRIIAGTNILNALLIVLAAGFGLGLGALGLDASQIFLAAALLNVLVAWYIFTLV
PEFVMRFITWVLVNTLYRVRADGTERIPWEGPALLVCNHVSFMDPLLLMAKLRRPVRFVM
YYRIFSIPVLSFVFRTARAIPIAGHKEDPAVLQQAYDAIDAALAAGEVVCVFPEGGLTAD
GEIAPFRPGVEKILARRPVPVVPMALRGLWGSVWSRRDSMLRRARLPRRFRARVELVVDA
PQEPAQVSAATLEARVRELRGELA