Protein Info for LRK54_RS08520 in Rhodanobacter denitrificans FW104-10B01

Annotation: ATP-dependent protease ATPase subunit HslU

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 TIGR00390: ATP-dependent protease HslVU, ATPase subunit" amino acids 4 to 447 (444 residues), 669.8 bits, see alignment E=9.7e-206 PF07728: AAA_5" amino acids 52 to 88 (37 residues), 24.7 bits, see alignment 6.4e-09 PF00004: AAA" amino acids 53 to 103 (51 residues), 29.8 bits, see alignment 2.3e-10 amino acids 242 to 336 (95 residues), 28.7 bits, see alignment E=4.8e-10 PF07724: AAA_2" amino acids 191 to 333 (143 residues), 89 bits, see alignment E=1.1e-28

Best Hits

Swiss-Prot: 68% identical to HSLU_SHEFN: ATP-dependent protease ATPase subunit HslU (hslU) from Shewanella frigidimarina (strain NCIMB 400)

KEGG orthology group: K03667, ATP-dependent HslUV protease ATP-binding subunit HslU (inferred from 68% identity to sfr:Sfri_3765)

Predicted SEED Role

"ATP-dependent hsl protease ATP-binding subunit HslU" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (447 amino acids)

>LRK54_RS08520 ATP-dependent protease ATPase subunit HslU (Rhodanobacter denitrificans FW104-10B01)
MSELTPREIVNELDRYIIGQHDAKRAVAVALRSRWRRMQLPAEMRNEITPKNILMIGPTG
VGKTEIARRLATLANAPFVKVEATKFTEVGYVGKDVESIIRDLADGAYKLTREQAIKRVR
SQAEDRAEDRILDALLPRRQTPPTDWSHDAPAAPAIDSDTRQKLRKQLREGALDEREIEL
DFAMNVGVEIMSPPGMEEMGAQLRQMFQNLGGAKTQNRKLAIKLARPLLIDEEAGKLLND
EEIRAQAMEAAEQNGIVFIDEIDKVAQRGDHGHAGVSREGVQRDLLPLVEGSTVSTKYGP
IKTDHMLFIASGAFSLAKPSDLIPELQGRLPIRVELSALSVDDFKRILREPQNALTKQYV
ALLGTEGVSIEFTDSGVDRLAEVAFQVNERTENIGARRLHTVMERLLEKISFEAADKSGE
KYLIDAEHVDKNLGSLARNEDLSRYIL