Protein Info for LRK54_RS07585 in Rhodanobacter denitrificans FW104-10B01

Annotation: monovalent cation/H+ antiporter subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 31 to 50 (20 residues), see Phobius details amino acids 81 to 101 (21 residues), see Phobius details amino acids 113 to 129 (17 residues), see Phobius details amino acids 132 to 151 (20 residues), see Phobius details amino acids 162 to 189 (28 residues), see Phobius details amino acids 207 to 231 (25 residues), see Phobius details amino acids 239 to 265 (27 residues), see Phobius details amino acids 280 to 301 (22 residues), see Phobius details amino acids 307 to 326 (20 residues), see Phobius details amino acids 334 to 356 (23 residues), see Phobius details amino acids 393 to 419 (27 residues), see Phobius details amino acids 440 to 468 (29 residues), see Phobius details amino acids 480 to 500 (21 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 129 to 437 (309 residues), 99.2 bits, see alignment E=1.3e-32

Best Hits

KEGG orthology group: K05561, multicomponent K+:H+ antiporter subunit D (inferred from 50% identity to dia:Dtpsy_1384)

Predicted SEED Role

"Na(+) H(+) antiporter subunit D" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (532 amino acids)

>LRK54_RS07585 monovalent cation/H+ antiporter subunit D (Rhodanobacter denitrificans FW104-10B01)
MSNQLIIAPIVLPLLVAALQLLVGERHRRTVLALSIGACVALVLLAAALMRTVSADGALA
AVYRIGDWPARFGIVLVADRLSALMVLLTTVLALAVLPYALGRWQHRGGHFQPLLQFLLM
GLNGAFLTGDLFNLFVFFEVLLAASYGLALHGSGARRVSAGLHYIAVNLTASMLFLLGVS
LIFGVTGTLNMAALAELIPHVPARTRALLHAGAALLGVAFLIKTAMWPLGFWLPRTYAAA
SPAVAAMFALMTKVGVYVLLRLGLLLFGDGAGPASAHFGSGWMLWGGVATVVAGTIGMLG
ARDLAKLAGYNVLISSGTLLGAIGLQQPAVTAGALAYLVISTLAIAALFLVVGLLASDGD
DETDDTLSLEPYEQAGETAANEGLYVQEDERRVVIAAPIAMLGVSFLACALLLAGLPPLS
GFLAKFALLAPMLDGGARSGAGVLFALVVVAGFCTVIALCRAGIQIFWVEPERIFPKVRL
VESASIAILLGLCLLLTVLAERPLRYLRDTAGQLHAPAGYIHAVLPPAEAAP