Protein Info for LRK54_RS07170 in Rhodanobacter denitrificans FW104-10B01

Annotation: peptidyl-dipeptidase Dcp

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 724 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF01432: Peptidase_M3" amino acids 270 to 717 (448 residues), 462.4 bits, see alignment E=1.2e-142

Best Hits

Swiss-Prot: 60% identical to DCP_ECOLI: Dipeptidyl carboxypeptidase (dcp) from Escherichia coli (strain K12)

KEGG orthology group: K01284, peptidyl-dipeptidase Dcp [EC: 3.4.15.5] (inferred from 74% identity to spe:Spro_2306)

MetaCyc: 60% identical to peptidyl-dipeptidase Dcp (Escherichia coli K-12 substr. MG1655)
Peptidyl-dipeptidase Dcp. [EC: 3.4.15.5]

Predicted SEED Role

"Dipeptidyl carboxypeptidase Dcp (EC 3.4.15.5)" in subsystem Protein degradation (EC 3.4.15.5)

Isozymes

Compare fitness of predicted isozymes for: 3.4.15.5

Use Curated BLAST to search for 3.4.15.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (724 amino acids)

>LRK54_RS07170 peptidyl-dipeptidase Dcp (Rhodanobacter denitrificans FW104-10B01)
MLRLRTIVIATTMALAACSQQPHEAANPPAPTAASSTATAMTSNPFYSASTLPFQAPPFD
KIHDTDYQPAIEEGMRQQLAEIEKIANDPAAPTFENTFVAMEKSGAMLHRVMAAFNAVTG
ANTNDTLQKVQEQEAPKLAAHEDAIHLDGKLFQRVQTIYDQRDTLKLDPESARLVEVVYK
NFVHAGAKLSDADKAKLKDLNKEESTLSTAFTNKLLAATKDAAPVIADKAQLAGLSDAEL
AAAAQAGKERKQDGKYVLTLQNTTQQPELQDLTDRATRQALFEASWTRAERGDANDTRKT
IERLAQIRAEQAKLLGYPDYAAWKLDDQMAKTPETALKFMQDLVPAVTARAKTEAGDIQA
VIDQQHGDFKLEPWDWNFYAEQVRKAKFDLDENQIKPYFELDDVLQNGVFYAANQLYGLT
FKERHDIPVYQPDMRVFEVFDQDGKSLALFYTDYFKRDNKGGGAWMDNLVTQSKLLGSKP
VIFNVCNFSKPAAGQPALLSFDDVTTMFHEFGHALHGIFADEQYPTLSGTNTARDFVEFP
SQFNEHWATDPKVFAHYAKNYQTGAPMPQALVDKMKKAGKFNKGYDMTELVAAALLDMNW
HMLGADAPLQDADQFEAAALKKDGIDLSYVPPRYRSSYFQHIWGNGYAAGYYAYLWTQML
ADDAFIGFKEHGGLTRENGDRFRAMVLSRGNTEELAKMYRDWRGHDPEIEPMLENRGLKD
APKK