Protein Info for LRK54_RS06505 in Rhodanobacter denitrificans FW104-10B01

Annotation: rod shape-determining protein RodA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 49 to 70 (22 residues), see Phobius details amino acids 81 to 99 (19 residues), see Phobius details amino acids 115 to 134 (20 residues), see Phobius details amino acids 141 to 159 (19 residues), see Phobius details amino acids 165 to 183 (19 residues), see Phobius details amino acids 189 to 207 (19 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 309 to 333 (25 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details TIGR02210: rod shape-determining protein RodA" amino acids 23 to 367 (345 residues), 403.6 bits, see alignment E=3.9e-125 PF01098: FTSW_RODA_SPOVE" amino acids 26 to 368 (343 residues), 344.9 bits, see alignment E=2.6e-107

Best Hits

Swiss-Prot: 51% identical to RODA_SHIFL: Peptidoglycan glycosyltransferase MrdB (mrdB) from Shigella flexneri

KEGG orthology group: K05837, rod shape determining protein RodA (inferred from 56% identity to mca:MCA0104)

MetaCyc: 51% identical to peptidoglycan glycosyltransferase MrdB (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Rod shape-determining protein RodA" in subsystem Bacterial Cytoskeleton or Peptidoglycan Biosynthesis

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (371 amino acids)

>LRK54_RS06505 rod shape-determining protein RodA (Rhodanobacter denitrificans FW104-10B01)
MIEALYARARRFARRLLSRPRIDLPLALGLFVLALTGLVTLYSAGDGNLALVGGQAARFV
LGGALLLVVSRIPPAVLRGWTPWMYAGSTALLVVVAILGEGRGSIRWLDLGFMRFQPSEL
LKLTMPMMVAWYLHPRQLPPGWKDIVMVGLLIAIPAGLIAEQPDLGTAVLVTAAGAFALF
LSGMAWWRIGLLLGAVAGMIPVGWHFMHQYQRERVLTLLNPESDPLGNGWHIIQSQIAVG
SGGVFGKGWLHSTQSRLDFLPEHTTDFIFAVFSEEFGLVGVAALLALYAFIIGRCLWIAM
EARDTYSRLLAGAIGMSFFVYVFVNGGMVAGMLPVVGVPLPLISYGGTSAVSLLTGFGVL
MSIHANRKMHL