Protein Info for LRK54_RS05160 in Rhodanobacter denitrificans FW104-10B01

Annotation: DegT/DnrJ/EryC1/StrS family aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 52% identical to FDTB_ANETH: dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase (fdtB) from Aneurinibacillus thermoaerophilus

KEGG orthology group: None (inferred from 74% identity to xop:PXO_00203)

MetaCyc: 52% identical to dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase (Aneurinibacillus thermoaerophilus L420-91)
RXN-12811 [EC: 2.6.1.90]

Predicted SEED Role

"Aminotransferase"

MetaCyc Pathways

dTDP-3-acetamido-α-D-fucose biosynthesis (4/5 steps found)
dTDP-α-D-ravidosamine and dTDP-4-acetyl-α-D-ravidosamine biosynthesis (4/6 steps found)
superpathway of dTDP-glucose-derived O-antigen building blocks biosynthesis (7/19 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.90

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (385 amino acids)

>LRK54_RS05160 DegT/DnrJ/EryC1/StrS family aminotransferase (Rhodanobacter denitrificans FW104-10B01)
MGPDVMQNAPAEAAPGDVPFLSLREVNARYADELKAAAARVIDSGWYVLGDELVAFEREF
AGWCGVRHAVGVGNGLDALSLILRGYKELGVLGEGDEVVVPGNTFIASFLAISENRLVPL
PVEPDAATFNLDPACVEAAIGPRTRAIMAVHLYGQLADMPALAALARRRGLLLIEDAAQA
HGALRDGRRAGTFGDAAAFSFFPAKNLGALGDGGAVVTGDVALARRVAALRNYGSEVKYR
HLCQGLNSRLDEMQAAMLRVKLKYLDADVAWRRRVAHRYRDGIRHPRIKLPDAVREEQHA
WHLFVVRCAERDALQRHLRAHGIQAQVHYPVPAHRQPAYPALRSARLPLTERLCDEVLSL
PLGPTLGDDGVARVIDACNAFGGGA