Protein Info for LRK54_RS02890 in Rhodanobacter denitrificans FW104-10B01

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 transmembrane" amino acids 14 to 35 (22 residues), see Phobius details amino acids 42 to 60 (19 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 122 to 140 (19 residues), see Phobius details amino acids 150 to 172 (23 residues), see Phobius details amino acids 192 to 216 (25 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details amino acids 328 to 349 (22 residues), see Phobius details amino acids 355 to 376 (22 residues), see Phobius details amino acids 394 to 415 (22 residues), see Phobius details amino acids 421 to 440 (20 residues), see Phobius details PF00324: AA_permease" amino acids 13 to 439 (427 residues), 390.3 bits, see alignment E=1.3e-120 PF13520: AA_permease_2" amino acids 14 to 430 (417 residues), 118.5 bits, see alignment E=3.7e-38

Best Hits

Swiss-Prot: 56% identical to YTNA_BACSU: Uncharacterized amino acid permease YtnA (ytnA) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 58% identity to bur:Bcep18194_B0065)

MetaCyc: 49% identical to phenylalanine:H+ symporter PheP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-56

Predicted SEED Role

"D-serine/D-alanine/glycine transporter" in subsystem Glycine and Serine Utilization or Pyruvate Alanine Serine Interconversions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (451 amino acids)

>LRK54_RS02890 amino acid permease (Rhodanobacter denitrificans FW104-10B01)
MTQTLQRQLTPRHITFMALGMCIGAGLFLGSASTIQLAGPSLLFAYLFGGTMIFIIMRAL
GEMAAHEPIAGSFSAYAHKYLGPFAGYLTGWNYWILMMGVGIAESTAVGIYMKAWFPASP
QWIWAFASVAMIGGLNLMAVKVYGELEFWFALIKVLTVVAMIAGGCAMIWLGWGNGGKPI
GLSNLWTHGGWFPNGITGMVLALPVLVFSFGGIETIGMAAAEAAQPERTIPRAVNSVIWR
ILIFYIGSLFVIMAIYPWNALGTQGSPFVTTFARLGIPQAAGLINFVVITAALSSFNSTM
FSGSRMLHSLATKGQAPMAMGRLSAQGVPVRGVLVTLVFLLFGVLMNYLVPGRIFGMMMS
ILAFNTVWTWGMVLVAHWRFRRQQPVPLAFRLRWFPLSSVVCLAFLAFVLVMLGYSADTR
VALYVGVIWLALLTVGYRVGGIEQRMRMASA