Protein Info for LRK54_RS02875 in Rhodanobacter denitrificans FW104-10B01

Annotation: M14 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00246: Peptidase_M14" amino acids 48 to 185 (138 residues), 65.8 bits, see alignment E=2.5e-22

Best Hits

KEGG orthology group: None (inferred from 49% identity to gvi:gll2474)

Predicted SEED Role

"Gll2474 protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (610 amino acids)

>LRK54_RS02875 M14 family metallopeptidase (Rhodanobacter denitrificans FW104-10B01)
MSLRRVLWCTLLGVAALSAHAAGPGATDWTTPAEAAQFRTTPSYADTLAYLQRLQRAAPG
VIRLETFGTTPQGRPMTVVIASAGGSFDPAAARAAHKPVVLLQAGIHPGEIEGKDAGLML
LRDIAVAGKVPHLLDQVVLVYIPVFNVDGHENASPYHRINQNGPERMGFRGQAQYLNLNR
DYVKADAPEMRAWLKLWQRWLPDFLIDVHTTDGADYQYDLTWYTEDPHKLDPALSAWQRD
AIVKHVMPAYEQRGHLASIYLEFKDGREPRKGIINFGSGPRFSTGYAALQNRPALLIETH
MLKPYANRVRAVYDLVELLLEQVGAHPAALLAATAQADAATIARAHDANARVALSFEPDP
QPTRFELKGYAFTLSHSDISGSEWIRYDPRTPKRYTIDNWNGLLPDVSIAPPAAYAVPAQ
WTTIIDRLDAHGIAYRRTERPLTIRAEGYQLDDPVWASKPFEGHLMLRDFRLRAVPREVT
LPAGSAIVPLDQRAANVAIELLEPQAPDSLLRWGFLDAVFEAKEYGEPRVVEQLARDMLA
RNPALKAAFAQKLHDDPAFAADSRARLMYFFERSPWYAAQNVGAYPVLRLDAAAWRQLAP
SAPAPSPSQP