Protein Info for LRK54_RS01525 in Rhodanobacter denitrificans FW104-10B01

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 transmembrane" amino acids 29 to 50 (22 residues), see Phobius details amino acids 60 to 83 (24 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 166 to 190 (25 residues), see Phobius details amino acids 198 to 219 (22 residues), see Phobius details amino acids 240 to 257 (18 residues), see Phobius details amino acids 276 to 301 (26 residues), see Phobius details amino acids 325 to 346 (22 residues), see Phobius details amino acids 376 to 394 (19 residues), see Phobius details amino acids 400 to 419 (20 residues), see Phobius details amino acids 431 to 450 (20 residues), see Phobius details amino acids 456 to 475 (20 residues), see Phobius details PF13520: AA_permease_2" amino acids 27 to 467 (441 residues), 191.6 bits, see alignment E=3.7e-60 PF00324: AA_permease" amino acids 33 to 457 (425 residues), 135.9 bits, see alignment E=2.6e-43 PF13906: AA_permease_C" amino acids 430 to 480 (51 residues), 40.1 bits, see alignment 4.9e-14

Best Hits

Swiss-Prot: 47% identical to YHDG_BACSU: Uncharacterized amino acid permease YhdG (yhdG) from Bacillus subtilis (strain 168)

KEGG orthology group: K03294, basic amino acid/polyamine antiporter, APA family (inferred from 73% identity to smt:Smal_1784)

Predicted SEED Role

"Amino acid transporters"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (494 amino acids)

>LRK54_RS01525 amino acid permease (Rhodanobacter denitrificans FW104-10B01)
MLKQLLARKTDFNEPDDTHGPTLRRTLGPWGLTALGIGAVIGGGIFVITGQAAADHAGPA
VILSFILAAICSTFTALCYAEFATLIPVSGSAYSYAYATLGELMAWFIGWNLVLEYGVSA
SAVAVSWTGYFLSLLQHIGSTFNMDLSLPAALTNAPLAFTADHQLVATGALFNLPAVVLI
LLLTWICYVGIRESSLANAAMVALKVGLITLVIVVGWRYVDPSNWHPFVPESQGHYKYGW
GGVLRGAAMVFFAYIGFEATSVAAQESRNPQRDLPIGILASLAVCTVLYIAMAAVMTGLT
SYTLLGTDEPVVTALHGHPQLEWLRWLVEVGALLGLSSVVLVMIIAQPRIFMIMGRDGML
PKVFTRIHPRYRTPHLNTLITGAGIALLAAIFPLDVLGDLVSMGTLIAFMAVCAGVWILR
HTRPELPRTFRVPFAPVICTLGILSCLALLSTMAWYNWSLMIVWTLLGLVIYFSYGNRHS
HLRSPVADASSTDA