Protein Info for LRK54_RS00915 in Rhodanobacter denitrificans FW104-10B01
Annotation: LysR substrate-binding domain-containing protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 38% identical to CBL_KLEAE: HTH-type transcriptional regulator cbl (cbl) from Klebsiella aerogenes
KEGG orthology group: None (inferred from 60% identity to psu:Psesu_0461)Predicted SEED Role
"Cys regulon transcriptional activator CysB" in subsystem Cysteine Biosynthesis or DNA-binding regulatory proteins, strays
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (331 amino acids)
>LRK54_RS00915 LysR substrate-binding domain-containing protein (Rhodanobacter denitrificans FW104-10B01) MTLTQLRYLVAIADSGLNITLAAERVHATQPGLSKQLKQLEDELGFQLFVRKGKSLDAVS QAGRHVLERARAILAEAANIRAIAANLRNEAHGELRIATTHTQARFALPAAIGALNQRYP QVSVHLQPGRDGEVLAQLEAGRVDLAVISTAGAPPPIGFALPAYRWQRVIVAPREHPLAT SGRQPSLDELATLPLVSYDSSLKADSSLRRAFEARGLRPQIAMTAGDADLIKTYVRTGLG IGVLAEMAMQDGDTDLRALPADHLFPQCTTWIVLRRESVLREYVLEFITQFAPHLDRREV VRALAADTVPAEWSAVPHWRERSPAALPDAA