Protein Info for LRK54_RS00325 in Rhodanobacter denitrificans FW104-10B01

Annotation: ATP-binding cassette domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 673 PF00005: ABC_tran" amino acids 17 to 178 (162 residues), 73 bits, see alignment E=1.2e-23 amino acids 374 to 505 (132 residues), 78.6 bits, see alignment E=2.3e-25 PF12848: ABC_tran_Xtn" amino acids 217 to 298 (82 residues), 92.1 bits, see alignment E=5.8e-30 PF16326: ABC_tran_CTD" amino acids 606 to 667 (62 residues), 32.5 bits, see alignment E=2.5e-11

Best Hits

Predicted SEED Role

"Glutathione-regulated potassium-efflux system ATP-binding protein" in subsystem Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (673 amino acids)

>LRK54_RS00325 ATP-binding cassette domain-containing protein (Rhodanobacter denitrificans FW104-10B01)
MISFRHFALRRGSRLLLSDIDLVIQGGWRLGVIGRNGCGKSSLFAALQGTLEGDVGELEM
SGKLRLASVAQETPALPDAAIDYVLGGDEELAAAIRDEAEAGERGDMEAMAKAHHRIEEL
NGYDGRARAGRLLHGLGFSPETHERAVQEFSGGWRGRLNLARALMCPSDLLLLDEPTNHL
DLDAVLWLEEWLRRYQGTLLIISHDREFLDGVITHTLHLNDGKAKLYTGNYSAFERLRAE
QLRQQQISHEREQAERAHLQSFIDRFKAKATKAKQAQSRMKRLEKLAGTEAVRAERPFSF
QFAAPGRLPDSMLQLEDITAGYELLPLPAGERVGVRGHGRGEDGSERASMDPSASPSPSP
HASPRRGEAVNVVLSDVRFSIEAGERIGLLGPNGAGKSTLVKTLVGELEPFGGERKVHKD
LKIGYFAQHTVESLREGSSPLDHLLDKAPGVATQVMRDFLGTWDFAGDRAFESVDGFSGG
ERARLALALIAWDKPNLLLLDEPTNHLDLDMREALADALADFDGALVLVSHDRHLLGMVC
DSFWRVADGEVAPFDGDLDDYARWLKTRSTASKKTAKPVVAKMAEVSPEQRRRQAAAQRE
NEKAARQRVKKIETRTAGIDTELAALEAGLADPATYNGPTSEMMRLGQRQTELRHEKEAL
ETEWLALVEQLEA