Protein Info for JOY50_RS07735 in Pseudomonas sp. BP01

Annotation: cytosine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 32 to 52 (21 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 100 to 125 (26 residues), see Phobius details amino acids 137 to 161 (25 residues), see Phobius details amino acids 167 to 185 (19 residues), see Phobius details amino acids 197 to 221 (25 residues), see Phobius details amino acids 241 to 263 (23 residues), see Phobius details amino acids 275 to 294 (20 residues), see Phobius details amino acids 300 to 319 (20 residues), see Phobius details amino acids 326 to 348 (23 residues), see Phobius details amino acids 354 to 376 (23 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details amino acids 434 to 451 (18 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 18 to 439 (422 residues), 173.4 bits, see alignment E=3.9e-55

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 98% identity to ppg:PputGB1_2252)

Predicted SEED Role

"Cytosine/purine/uracil/thiamine/allantoin permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (470 amino acids)

>JOY50_RS07735 cytosine permease (Pseudomonas sp. BP01)
MTSAANSAPLIEKHTIGYVPPQDRHGKVRDLFTLWFGGNIAPLPIVTGALGVQLFHLNLI
WGIVAILVGHLVGGVLMALHSAQGPQMGIPQMIQSRAQFGTLGALLVVVIAGVMYIGFFA
SNIVLAGKSLHGVVDTVPVPVGIVIGALGSGIIGIIGYRFIHVLNRIGTWVLGIGIVVGF
GYIFTHVQSDDFLTRGSFNLAGWLATVSLAALWQIAFAPYVSDYSRYLPADVKVSSTFWT
TYLGSALGSSLSFIFGAVAVLAIPAGMDTMDAVKLATGTLGPIMLVLFLLSVISHNALNL
YGAVLSIITLVQTFAYRWIPTAKSRAVLSLIVLSACCVVAVFASADFIGHFVDMVLVLLV
VLVPWTAINLIDFYVIHKGDYDIQSIFQVDGGIYGRYNPQALIAYAVGIVVQIPFMNTPL
YVGPISEHINGADLSWLVGLAITSPLYWWLASRDSAYRRRQTSAKLAMGH