Protein Info for IKLFDK_24350 in Pseudomonas aeruginosa PA14

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 48 to 67 (20 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 105 to 127 (23 residues), see Phobius details amino acids 139 to 159 (21 residues), see Phobius details amino acids 165 to 186 (22 residues), see Phobius details amino acids 199 to 219 (21 residues), see Phobius details amino acids 230 to 248 (19 residues), see Phobius details amino acids 269 to 291 (23 residues), see Phobius details amino acids 304 to 323 (20 residues), see Phobius details amino acids 335 to 353 (19 residues), see Phobius details amino acids 359 to 382 (24 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details amino acids 464 to 484 (21 residues), see Phobius details PF06609: TRI12" amino acids 10 to 409 (400 residues), 43.7 bits, see alignment E=2.2e-15 TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 15 to 419 (405 residues), 252.3 bits, see alignment E=4.6e-79 PF07690: MFS_1" amino acids 18 to 410 (393 residues), 183.4 bits, see alignment E=8.7e-58 PF00083: Sugar_tr" amino acids 48 to 181 (134 residues), 64 bits, see alignment E=2e-21

Best Hits

KEGG orthology group: None (inferred from 99% identity to pag:PLES_02431)

Predicted SEED Role

"Drug resistance transporter, EmrB/QacA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (501 amino acids)

>IKLFDK_24350 MFS transporter (Pseudomonas aeruginosa PA14)
MSDLAQNPPAVRTVLAGLMLSIFLSALDQTIVAVSLPAISADFADLDLLAWVISAYMVAM
TVSMPIYGKLGDLYGRRRLMLFAIVVFTAASLLCGLAQSMGQLVLARVLQGVGAGGLMAV
SQAIIGDIVPPRERGRYQGYFSSMYAIASVAGPVLGGLLTEYLSWRWVFWINLPIGLLAL
AISRRTLVGLPVPRRQPVIDYLGIVLMVVGLTALLLAITQIGQGAAWSDPALLGLFALAA
LALLLFVAQERRFREPLVPMQLFAVRAATLSWLVAFFASFQAISLTVLVPLRYQSVTGAG
ADSAALHLLPLVMGLPLGAYCCGRLTASLGRYKPLILLGAVLLPCGIAGLALVPVGDHWL
SGLCMLLTGIAIGTQFPTSLVAAQNAVEQRHIGVATSNATLFRSLGGAVGVALMSAILLA
LLKHLRIGGGLDQGFSESALLSSLDAASGPARVILQHVLADAFKVLFLVNAAVALLGLAV
ASALPDMTLRGRGATQPTAGE