Protein Info for IKLFDK_06790 in Pseudomonas aeruginosa PA14

Annotation: carbonate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 902 transmembrane" amino acids 67 to 85 (19 residues), see Phobius details amino acids 90 to 107 (18 residues), see Phobius details amino acids 251 to 272 (22 residues), see Phobius details amino acids 278 to 304 (27 residues), see Phobius details amino acids 696 to 720 (25 residues), see Phobius details amino acids 727 to 745 (19 residues), see Phobius details amino acids 766 to 789 (24 residues), see Phobius details amino acids 801 to 818 (18 residues), see Phobius details amino acids 839 to 856 (18 residues), see Phobius details amino acids 876 to 893 (18 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 13 to 78 (66 residues), 61.3 bits, see alignment 1.7e-20 TIGR01494: HAD ATPase, P-type, family IC" amino acids 90 to 353 (264 residues), 138.2 bits, see alignment E=1.5e-44 amino acids 607 to 728 (122 residues), 121 bits, see alignment E=2.4e-39 PF00122: E1-E2_ATPase" amino acids 120 to 312 (193 residues), 173.7 bits, see alignment E=8.6e-55 PF00702: Hydrolase" amino acids 329 to 650 (322 residues), 61.9 bits, see alignment E=3.4e-20 PF13246: Cation_ATPase" amino acids 393 to 477 (85 residues), 69.4 bits, see alignment E=6.6e-23 PF08282: Hydrolase_3" amino acids 621 to 682 (62 residues), 29.3 bits, see alignment 2.3e-10 PF00689: Cation_ATPase_C" amino acids 721 to 893 (173 residues), 172.7 bits, see alignment E=2e-54

Best Hits

KEGG orthology group: None (inferred from 100% identity to pau:PA14_45970)

Predicted SEED Role

"Ca ion P-type ATPase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (902 amino acids)

>IKLFDK_06790 carbonate dehydratase (Pseudomonas aeruginosa PA14)
MNGIPPLSSRDAHASPPQRVLERLHSSAAGLDADEAARRLAAHGYNRLPAPKRQGPLLRL
LRQFHNVLLYMMLFASLVTALLGFWVDSAVILLAVVVNALIGFVQEGKAANALDAIRDML
SLHALVLRDGQRQALDAERLVPGDVVLLASGDRVPADLRLFETKNFHVDESALTGESVPV
EKGCVAVAIDALLGDRRCMAYSGTLVTSGQARGVVVATAGDTELGRIGTLLREVRTLATP
LLRQIASFSRWLALAILLLAGATFVLGTLWQGQPMVDMFMLVVALTASAIPEGLPAIMTV
ILALGVQRMARRNAIVSRLPAVETLGSVTVICSDKTGTLTRNEMTVQRIVTADQVIEVSG
AGYAPLGGFSHNGEGLDPAGRDDLQEIGRAALLCNEARLHQEGEAWQLEGDPTEGALLSL
GLKLGLDPQALAAERPRSDAIPFESEHRFMATLHHDHAGQAMVYLKGAPERILDMCEAER
VGDSVRSLDPDYWRRLATDTAARGLRLLAIARRAMPAEQRTLDFADVEHGFTLLALVGII
DPPREEAVAAVAECQAAGIAVKMITGDHVDTARAIGAMLGIGIDRPALTGAEIELLDDQR
LREVLPGVDVFARASPEHKLRLVQALQASGEVVAMTGDGVNDAPALKRADVGVAMGNKGT
EAAKEAAEVVLADDNFATIANAVREGRAVYDNLKKFILFMLPTNGGEALIVIAAILFQLT
LPMTPAQILWINMVTSSTLGLALAFDPAERGLMQRPPRPPAEPLLSLFFVWRVLLVSLLM
MAGALGLFLWELEHGTGLERARTMAVNSVVVCEMFYLLNSRHIYDSVLSREGLFGNRQVL
LAIAACVVLQLLYTYAPPLQALFGSVGLAPGEWARVLLAGLGLFCVAELEKWLCRRVRAR
QA