Protein Info for IAI47_21850 in Pantoea sp. MT58

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR02417: D-fructose-responsive transcription factor" amino acids 8 to 333 (326 residues), 403 bits, see alignment E=5.2e-125 PF00356: LacI" amino acids 8 to 56 (49 residues), 59.2 bits, see alignment 5.3e-20 PF00532: Peripla_BP_1" amino acids 68 to 265 (198 residues), 54.6 bits, see alignment E=2.5e-18 PF13407: Peripla_BP_4" amino acids 71 to 280 (210 residues), 38.1 bits, see alignment E=2.7e-13 PF13377: Peripla_BP_3" amino acids 184 to 333 (150 residues), 62.6 bits, see alignment E=1.1e-20

Best Hits

Swiss-Prot: 71% identical to SCRR_KLEPN: Sucrose operon repressor (scrR) from Klebsiella pneumoniae

KEGG orthology group: K03484, LacI family transcriptional regulator, sucrose operon repressor (inferred from 94% identity to pva:Pvag_pPag10152)

Predicted SEED Role

"Sucrose operon repressor ScrR, LacI family" in subsystem Sucrose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (334 amino acids)

>IAI47_21850 LacI family DNA-binding transcriptional regulator (Pantoea sp. MT58)
MRKTKRVTISDIAGLAGVSKATASLVLNGRGEELRVAKETRERVLTLAREHHYQPSIHAR
MLHDARSHTLGLVVPEITNHGFAAFSHALENLCRASGLQLLISCTDENAGQEMVVVNNLV
ARQVDGLIVASSMLTDSDYVSLSEQLPVLLFDRTMNNTKLPWVITDSITPTAELVEKLAR
ACPEEIYFMGGQSDLSPTQNRLAGFREGLARAGVTLQPEWIIQGNYHPGSGYEMFAALCN
RLGRPPKAMFTAACGLLEGVLRYMSEHSLLTSDIRIASFDDHYLYDSLSIPIDTVEQNVP
ALAQACFTMLTTMIAGEDPVNSQLILPATLRLRV