Protein Info for IAI47_21775 in Pantoea sp. MT58

Annotation: excinuclease ABC subunit UvrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 844 PF17755: UvrA_DNA-bind" amino acids 170 to 233 (64 residues), 39.4 bits, see alignment 1.7e-13 PF13304: AAA_21" amino acids 675 to 783 (109 residues), 28.1 bits, see alignment E=5.1e-10

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 91% identity to pva:Pvag_pPag10127)

Predicted SEED Role

"Excinuclease ABC subunit A paralog of unknown function" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (844 amino acids)

>IAI47_21775 excinuclease ABC subunit UvrA (Pantoea sp. MT58)
MTDQRNAERNRADEHIDPYVSVQGARTHNLKDVSFRFPRNAMVVFTGVSGSGKSSLAFDT
LYAEAQRRFIESVSPHARRLIDQAAAPDVDNIDGLPPAVALQQSRAGAQERSTVGSLTRI
SVTLRLLFSRAGARPDGVPFMTADYFSPNNPEGACPHCQGLGSVHTVKTDSMVQDDSLSI
RQGAIASWPRGWHNKNLRSILETLGYDVDAPWHTLSSRDQQWILLTDEQPSVPIFIGLNA
EQREEALAAGEEPAYTGTYTSAAKIVLQSYSGGSETTKKRLARYVTVTPCSACHGKRLNR
DALSVTFAGYDIASLSELSVSALAELLKPYADGTSSNLPVEAALREAVIRMTSDISMRLQ
QLDTLGLGHLAPGRRTTQLSSGELQRVRLATQLISRLFGVLYVLDEPSAGLHPDDVKALL
TSLKNLVRAGNSLVVVEHNMDLIAEADWLIEVGPGPGTHGGEIVYNGEPAGLKNIASPTS
DYLFSRSYTGLRQRRPAESWLRFEQVHCNNISAMDIAIPLARMTAVTGVSGSGKSTLLNR
VLPEMLGRFDKIADSDEGEEEDLVADVRGQVVSGSDAIGRLVRIDQRPIGRTPRSNLATY
TGFFDIIRRLFAETPAAKAKGFSASRFSFNLPAGRCPACEGQGQISIELLFMPSATATCS
VCAGGRYNPDTLEVKWNNLTIADVLALTVDDATALFHAYDGIQRSLKALTSLGLGYLTLG
QPATELSGGECQRIKLAWELQRLQRTPTLYLLDEPSTGLHPSDMDKLLIVLDELVKRGHT
VIMAEHTMRIVAEADWVIDLGPGSGLRGGKIVSSGLPEEVSLSAESLTAPWLSAQLKKRA
GDPD